Synthesis, and biological evaluation of some 4-thiazolidinones

被引：0
|
作者：
Amir, M [1 ]
Azam, F [1 ]
机构：
[1] Hamdard Univ, Fac Pharm, Dept Pharmaceut Chem, New Delhi 110062, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2004年 / 14卷 / 02期
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D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis and biological activities (antiinflammatory, antibacterial and antifungal) of a number of 2,3-substituted 4-thiazolidinone derivatives are described. The compounds showed antiinflammatory activity ranging from 61.53% to 83.07% whereas reference drug ibuprofen showed 83.07% inhibition at 100 mg/kg oral dose in this test. All these compounds showed significant antibacterial and antifungal activity when compared with standard drugs amikacin and fluconazole.
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页码：119 / 122
页数：4
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