Bioactive pyranoxanthones from the roots of Calophyllum blancoi

被引：46
|
作者：
Shen, YC
Wang, LT
Khalil, AT
Chiang, LC
Cheng, PW
机构：
[1] Natl Sun Yat Sen Univ, Inst Marine Resources, Kaohsiung 80424, Taiwan
[2] Kaohsiung Med Univ, Kaohsiung, Taiwan
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 2005年 / 53卷 / 02期
关键词：
Calophyllum blancoi; Guttiferae; pyranoxanthones; blancoxanthone; antiviral activity;
D O I：
10.1248/cpb.53.244
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Phytochemical investigation of the roots of Calophyllum blancoi growing in Taiwan resulted in the isolation of three new pyranoxanthones, blancoxanthone (1), acetyl blancoxanthone (2) and 3-hydroxyblancoxanthone (3), in addition to two known pyranoxanthones, pyranojacaeubin (4) and caloxanthone (5). Structural characterization of the isolated compounds was determined by spectral analyses especially 2-D NMR. Biological study of the isolated xanthones revealed that blancoxanthone (1) exhibited significant anti-coronavirus activity.
引用
收藏
页码：244 / 247
页数：4
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