Fulminant granulomatosis with polyangiitis presenting with diffuse alveolar haemorrhage following COVID-19

被引:7
|
作者
Lind, Eric [1 ,2 ]
Jameson, Andrew [1 ,2 ]
Kurban, Esaw [1 ,2 ]
机构
[1] Michigan State Univ, Coll Human Med, Mercy Hlth St Marys Div Infect Dis, Grand Rapids, MI USA
[2] Michigan State Univ, Coll Human Med, Dept Med, Grand Rapids, MI USA
关键词
infectious diseases; vasculitis; respiratory medicine; renal medicine;
D O I
10.1136/bcr-2021-242628
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 40-year-old man developed granulomatosis with polyangiitis (GPA) following a mild case of COVID-19. Initially, he experienced mild migrating joint pain for 2 months prior to testing positive for SARS-CoV-2 but dramatically worsened following resolution of his infection. The pain continued to progress until he suddenly develope haemoptysis, prompting him to present to a local hospital. The diagnosis of diffuse alveolar haemorrhage secondary to GPA was confirmed with labs, imaging and histopathology. Precipitous deterioration of GPA with concurrent COVID-19 infection indicates a possible temporal relationship. Since the onset of the pandemic, SARS-CoV-2 has been anecdotally associated with the development of various connective tissue disorders. The overlapping clinical presentations and similar appearance on lung imaging present clinicians with a diagnostic challenge. This underscores the importance of having a high index of suspicion of autoimmune diagnoses in patients who present with new or worsening findings following a COVID-19 infection.
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页数:3
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