Fulminant granulomatosis with polyangiitis presenting with diffuse alveolar haemorrhage following COVID-19

被引:7
|
作者
Lind, Eric [1 ,2 ]
Jameson, Andrew [1 ,2 ]
Kurban, Esaw [1 ,2 ]
机构
[1] Michigan State Univ, Coll Human Med, Mercy Hlth St Marys Div Infect Dis, Grand Rapids, MI USA
[2] Michigan State Univ, Coll Human Med, Dept Med, Grand Rapids, MI USA
关键词
infectious diseases; vasculitis; respiratory medicine; renal medicine;
D O I
10.1136/bcr-2021-242628
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 40-year-old man developed granulomatosis with polyangiitis (GPA) following a mild case of COVID-19. Initially, he experienced mild migrating joint pain for 2 months prior to testing positive for SARS-CoV-2 but dramatically worsened following resolution of his infection. The pain continued to progress until he suddenly develope haemoptysis, prompting him to present to a local hospital. The diagnosis of diffuse alveolar haemorrhage secondary to GPA was confirmed with labs, imaging and histopathology. Precipitous deterioration of GPA with concurrent COVID-19 infection indicates a possible temporal relationship. Since the onset of the pandemic, SARS-CoV-2 has been anecdotally associated with the development of various connective tissue disorders. The overlapping clinical presentations and similar appearance on lung imaging present clinicians with a diagnostic challenge. This underscores the importance of having a high index of suspicion of autoimmune diagnoses in patients who present with new or worsening findings following a COVID-19 infection.
引用
收藏
页数:3
相关论文
共 50 条
  • [31] Granulomatosis with polyangiitis presenting as high fever with diffuse alveolar hemorrhage and otitis media: A case report
    Li, Xiao-Jie
    Yang, Liu
    Yan, Xiao-Feng
    Zhan, Chu-Ting
    Liu, Jiang-Hua
    WORLD JOURNAL OF CLINICAL CASES, 2021, 9 (10) : 2344 - 2351
  • [32] Microscopic Polyangiitis Presenting as Diffuse Alveolar Hemorrhage
    Rothweiler, Stephanie
    Liu, Shiguang
    Makary, Raafat F.
    Awad, Alaa S.
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2022, 33 (11): : 902 - 902
  • [33] Eosinophilic granulomatosis with polyangiitis after COVID-19: A case report
    Karampoor, Sajad
    Afrashteh, Fatemeh
    Rahmani, Shahrzad
    Laali, Azadeh
    RESPIRATORY MEDICINE CASE REPORTS, 2022, 38
  • [34] RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS IN THE SETTING OF GRANULOMATOSIS WITH POLYANGIITIS AND COVID-19
    Davis, Kristin
    Peng, Charles
    CHEST, 2022, 162 (04) : 856A - 856A
  • [35] Granulomatosis with polyangiitis mimicking COVID-19 pneumonia: A case report
    Basnet, Arjun
    Kansakar, Sajog
    Sharma, Nava Raj
    Gautam, Sudarshan
    Lamichhane, Saral
    Tiwari, Kripa
    Pokhrel, Madalasa
    Singh, Sehajpreet
    CLINICAL CASE REPORTS, 2023, 11 (10):
  • [36] Y Covid-19 and granulomatosis with polyangiitis. Autopsy report
    Mnikhovich, M.
    Sidorova, O.
    Shiripenko, I.
    Bezuglova, T.
    Romanov, A.
    Sotnikova, T.
    Mnikhovich, M.
    Polushkina, T.
    Pastukhova, D.
    VIRCHOWS ARCHIV, 2022, 481 (SUPPL 1) : S188 - S188
  • [37] A case of eosinophilic granulomatosis with polyangiitis associated with diffuse alveolar haemorrhage: A case report and case-based review
    Kawaguchi, Rira
    Usagawa, Hirohisa
    Miyawaki, Yoshia
    Oiwa, Hiroshi
    MODERN RHEUMATOLOGY CASE REPORTS, 2024, 8 (02) : 398 - 403
  • [38] A CASE OF GRANULOMATOSIS OF POLYANGIITIS PRESENTING WITH COVID-19 INFECTION: FALSE-POSITIVITY OR CO-EXISTENCE?
    Gokce, Ibrahim
    Sak, Mehtap
    Guven, Sercin
    Pul, Serim
    Alpay, Harika
    PEDIATRIC NEPHROLOGY, 2021, 36 (10) : 3415 - 3416
  • [39] Second COVID-19 infection in a patient with granulomatosis with polyangiitis on rituximab
    Friedman, Marcia A.
    Winthrop, Kevin L.
    ANNALS OF THE RHEUMATIC DISEASES, 2021, 80 (08) : 1102 - 1104
  • [40] A Distinctive Encounter With Diffuse Alveolar Hemorrhage in Granulomatosis With Polyangiitis and Pneumonia
    Shrestha, Shrijan
    Rai, Pragya
    Kayastha, Gyan
    CLINICAL CASE REPORTS, 2025, 13 (01):