Fulminant granulomatosis with polyangiitis presenting with diffuse alveolar haemorrhage following COVID-19

被引:7
|
作者
Lind, Eric [1 ,2 ]
Jameson, Andrew [1 ,2 ]
Kurban, Esaw [1 ,2 ]
机构
[1] Michigan State Univ, Coll Human Med, Mercy Hlth St Marys Div Infect Dis, Grand Rapids, MI USA
[2] Michigan State Univ, Coll Human Med, Dept Med, Grand Rapids, MI USA
关键词
infectious diseases; vasculitis; respiratory medicine; renal medicine;
D O I
10.1136/bcr-2021-242628
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 40-year-old man developed granulomatosis with polyangiitis (GPA) following a mild case of COVID-19. Initially, he experienced mild migrating joint pain for 2 months prior to testing positive for SARS-CoV-2 but dramatically worsened following resolution of his infection. The pain continued to progress until he suddenly develope haemoptysis, prompting him to present to a local hospital. The diagnosis of diffuse alveolar haemorrhage secondary to GPA was confirmed with labs, imaging and histopathology. Precipitous deterioration of GPA with concurrent COVID-19 infection indicates a possible temporal relationship. Since the onset of the pandemic, SARS-CoV-2 has been anecdotally associated with the development of various connective tissue disorders. The overlapping clinical presentations and similar appearance on lung imaging present clinicians with a diagnostic challenge. This underscores the importance of having a high index of suspicion of autoimmune diagnoses in patients who present with new or worsening findings following a COVID-19 infection.
引用
收藏
页数:3
相关论文
共 50 条
  • [21] Eosinophilic granulomatosis with polyangiitis after COVID-19 vaccination
    Chan-Chung, C.
    Ong, C. S.
    Chan, L. L.
    Tan, E. K.
    QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 2021, 114 (11) : 807 - 809
  • [22] COVID-19 and granulomatosis with polyangiitis (GPA): a diagnostic challenge
    Shenavandeh, Saeedeh
    Sefidbakht, Sepideh
    Iranpour, Pooya
    Teimouri, Arash
    Hooshmandi, Sedighe
    Hooshmandi, Etrat
    Athari, Mohammadjavad
    RHEUMATOLOGY, 2020, 59 (08) : 2170 - 2171
  • [23] DIFFUSE ALVEOLAR HEMORRHAGE IN THE SETTING OF SERONEGATIVE GRANULOMATOSIS WITH POLYANGIITIS
    Jaroenpuntaruk, Valerie
    Nguyen, Taylor
    Morris, Michael A.
    Carter, David
    CHEST, 2023, 164 (04) : 5671A - 5672A
  • [24] Granulomatosis with Polyangiitis with Peripheral Eosinophilia and Diffuse Alveolar Hemorrhage
    Haris, N.
    Ladzinski, A.
    Brooks, J.
    Patel, P. P.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2021, 203 (09)
  • [25] CATASTROPHIC DIFFUSE ALVEOLAR HEMORRHAGE DUE TO GRANULOMATOSIS WITH POLYANGIITIS
    Boshara, Peter
    Kanitkar, Amaraja A.
    CHEST, 2022, 162 (04) : 2228A - 2228A
  • [26] Alveolar haemorrhage in eosinophilic granulomatosis and polyangiitis (Churg-Strauss)
    L. Yalakki Jagadeesh
    S. R. Sangle
    H. Verma
    D. D’Cruz
    Clinical Rheumatology, 2014, 33 : 1177 - 1179
  • [27] Alveolar haemorrhage in eosinophilic granulomatosis and polyangiitis (Churg-Strauss)
    Jagadeesh, L. Yalakki
    Sangle, S. R.
    Verma, H.
    D'Cruz, D.
    CLINICAL RHEUMATOLOGY, 2014, 33 (08) : 1177 - 1179
  • [28] A Case of Diffuse Alveolar Hemorrhage Secondary to Granulomatosis With Polyangiitis
    Smith, C.
    Alon, M.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2024, 209
  • [29] Granulomatosis with polyangiitis presenting as high fever with diffuse alveolar hemorrhage and otitis media: A case report
    Xiao-Jie Li
    Liu Yang
    Xiao-Feng Yan
    Chu-Ting Zhan
    Jiang-Hua Liu
    World Journal of Clinical Cases, 2021, 9 (10) : 2344 - 2351
  • [30] Granulomatosis with Polyangiitis Presenting as Refractory Chronic Cough, Manifesting by Massive Alveolar Haemorrhage - A Rare Case Report
    Al Zaidi, Areej
    Al Zahrani, Abdullah M.
    Alzahrani, Zeyad
    INTERNATIONAL MEDICAL CASE REPORTS JOURNAL, 2021, 14 : 669 - 673