New four-component Ugi-type reaction. Synthesis of heterocyclic structures containing a pyrrolo[1,2-a][1,4]diazepine fragment

被引：42

作者：

Ilyn, AP

Trifilenkov, AS

Kuzovkova, JA

Kutepov, SA

Nikitin, AV

Ivachtchenko, AV

机构：

[1] ChemDiv Inc, San Diego, CA 92121 USA

[2] Chem Divers Res Inst, Dept Organ Chem, Moscow 114401, Russia

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 70卷 / 04期

关键词：

D O I：

10.1021/jo048204b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We present a convenient synthesis of novel heterocyclic structures containing pyrrolo[1,2-a] [1,4]diazepine fragment using a novel modification of four-component Ugi condensation. We demonstrate the usefulness and versatility of the developed approach for the synthesis of variously substituted compounds and discuss the scope and limitations of the chemistry involved.

引用

页码：1478 / 1481

页数：4

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