Concise diastereospecific pyrrolo[1,2-a][1,4]benzodiazepinone synthesis

被引：13
|
作者：
Mucedda, Mauro [1 ]
Muroni, Daniele [1 ]
Saba, Antonio [1 ]
Manassero, Carlo [2 ]
机构：
[1] Univ Sassari, Fac Sci, Dipartimento Chim, I-07100 Sassari, Italy
[2] Univ Milan, Fac Sci, Dipartmento Chim Struct & Stereochim Inorgan, I-20133 Milan, Italy
来源：
TETRAHEDRON | 2007年 / 63卷 / 49期
关键词：
Benzodiazepines; diazo compounds; cascade process; Stevens[1,2]-shift;
D O I：
10.1016/j.tet.2007.09.062
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A concise synthesis of the novel pyrrolo[1,2-a]benzodiazepine system, by using the metallo carbenoid/spiro-[6,5]-ammonium ylide/Stevens [1,2]-shift with ring-expansion approach, was reported. The overall cascade process resulted stereospecific. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码：12232 / 12238
页数：7
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