Teuchamaedol A, a new neo-clerodane diterpenoid from the aerial parts of Teucrium chamaedrys

被引：0
|
作者：
Kurimoto, Shin-ichiro [1 ,2 ]
Wakabayashi, Koji [1 ]
Sasaki, Yu F. [3 ,4 ]
Nakamura, Takanori [4 ]
Kubota, Takaaki [1 ,5 ]
机构：
[1] Showa Pharmaceut Univ, 3-3165 Higashi Tamagawagakuen, Machida, Tokyo 1948543, Japan
[2] Showa Univ, Sch Pharm, Shinagawa Ku, 1-5-8 Hatanodai, Tokyo 1428555, Japan
[3] Hachinohe Natl Coll Technol, Fac Chem & Biol Engn, Lab Genotoxic, 16-1 Tamonoki Uwanotai, Hachinohe, Aomori 0391192, Japan
[4] Himeji Dokkyo Univ, Fac Pharmaceut Sci, 7-2-1 Kamiohno, Himeji, Hyogo 6708524, Japan
[5] Okayama Univ, Fac Med Dent & Pharmaceut Sci, Kita Ku, 1-1-1 Tsushima Naka, Okayama 7008530, Japan
来源：
TETRAHEDRON LETTERS | 2022年 / 100卷
关键词：
neo-Clerodane; Diterpenoid; Teucrium chamaedrys; Lamiaceae; CLERODANE DITERPENOIDS; PORTULACA-GRANDIFLORA; GERMANDER; HEPATITIS;
D O I：
10.1016/j.tetlet.2022.153890
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new neo-clerodane diterpenoid, teuchamaedol A (1) was isolated from the EtOAc-soluble materials of the aerial parts of Teucrium chamaedrys. The structure of 1 was elucidated on the basis of spectral data. The absolute configuration of 1 was determined by modified Mosher's method. Teuchamaedol A (1) is the first neo-clerodane diterpenoid possessing a tetrahydrofuran moiety without additional oxygen function. (C) 2022 Elsevier Ltd. All rights reserved.
引用
收藏
页数：3
相关论文
共 50 条
  • [21] A neo-clerodane diterpenoid from Scutellaria baicalensis
    Hussein, AA
    delaTorre, MC
    Jimeno, ML
    Rodriguez, B
    Bruno, M
    Piozzi, F
    Servettaz, O
    PHYTOCHEMISTRY, 1996, 43 (04) : 835 - 837
  • [22] A neo-clerodane diterpenoid from Scutellaria seleriana
    Esquivel, B
    Calderón, JS
    Flores, E
    PHYTOCHEMISTRY, 1998, 47 (01) : 135 - 137
  • [23] A new neo-clerodane diterpenoid from Salvia gesneraeflora (Labiatae)
    Esquivel, B
    Flores, EA
    HETEROCYCLES, 2001, 55 (03) : 505 - 509
  • [24] New neo-clerodane diterpenoids with neurotrophic activity from the aerial parts of Salvia tiliifolia
    Fan, Min
    Bao, Ying
    Zhang, Zhi-Jun
    Zhang, Hong-Bin
    Zhao, Qin-Shi
    FITOTERAPIA, 2017, 123 : 44 - 50
  • [25] TEUPONXN: A NEO-CLERODANE DITERPENE FROM TEUCRIUM JAPONICUM
    Zhi Da MIN~1~*
    Chinese Chemical Letters, 1991, (05) : 371 - 372
  • [26] Neo-clerodane diterpenoids from three species of Teucrium
    Rodriguez, B
    delaTorre, MC
    Bruno, M
    Piozzi, F
    Vassallo, N
    Ciriminna, R
    Servettaz, O
    PHYTOCHEMISTRY, 1996, 43 (02) : 435 - 438
  • [27] NEO-CLERODANE DITERPENOIDS FROM TEUCRIUM-CANADENSE
    BRUNO, M
    PIOZZI, F
    SAVONA, G
    DELATORRE, MC
    RODRIGUEZ, B
    PHYTOCHEMISTRY, 1989, 28 (12) : 3539 - 3541
  • [28] NEO-CLERODANE DITERPENOIDS FROM TEUCRIUM-MICROPODIOIDES
    DELATORRE, MC
    RODRIGUEZ, B
    BRUNO, M
    SAVONA, G
    PIOZZI, F
    SERVETTAZ, O
    PHYTOCHEMISTRY, 1988, 27 (01) : 213 - 216
  • [29] NEO-CLERODANE DITERPENOIDS FROM TEUCRIUM-PYRENAICUM
    GARCIAALVAREZ, MC
    MARCO, JL
    RODRIGUEZ, B
    SAVONA, G
    PIOZZI, F
    PHYTOCHEMISTRY, 1982, 21 (10) : 2559 - 2562
  • [30] Phytotoxic neo-clerodane diterpenoids from the aerial parts of Scutellaria barbata
    Li, Hang-Ying
    Wei, Wen-Jun
    Ma, Kai-Liang
    Zhang, Jie-Yao
    Li, Ya
    Gao, Kun
    PHYTOCHEMISTRY, 2020, 171
12345