Carbocyclic 7-deazaguanine oxetanocin analogues

被引:0
|
作者
Wu, JY [1 ]
Schneller, SW
Seley, KL
De Clercq, E
机构
[1] Univ S Florida, Dept Chem, Tampa, FL 33620 USA
[2] Auburn Univ, Dept Chem, Auburn, AL 36849 USA
[3] Katholieke Univ Leuven, Rega Inst Med Res, B-3000 Louvain, Belgium
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D O I
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中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of two carbocyclic 7-deazaguanosine oxetanocins structurally modified at the C-3' center and lacking the C-2' hydroxymethylene group is described. Neither of these target compounds showed antiviral activity against a battery of DNA and RNA viruses.
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页码:757 / 763
页数:7
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