The synthesis of two carbocyclic 7-deazaguanosine oxetanocins structurally modified at the C-3' center and lacking the C-2' hydroxymethylene group is described. Neither of these target compounds showed antiviral activity against a battery of DNA and RNA viruses.
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Leicester Institute of Structural and Chemical Biology, Department of Molecular and Cell Biology, University of Leicester, LeicesterLeicester Institute of Structural and Chemical Biology, Department of Molecular and Cell Biology, University of Leicester, Leicester
Weldon C.
Behm-Ansmant I.
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IMoPA (Ingénierie Moléculaire et Physiopathologie Articulaire), Centre National de la Recherche Scientifique (CNRNRS), Biopôle de l'Université de Lorraine, Vandoeuvre-lès-NancyLeicester Institute of Structural and Chemical Biology, Department of Molecular and Cell Biology, University of Leicester, Leicester
Behm-Ansmant I.
Hurley L.H.
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College of Pharmacy, BIO5 Institute, University of Arizona, Tucson, AZ
University of Arizona Cancer Center, Tucson, AZLeicester Institute of Structural and Chemical Biology, Department of Molecular and Cell Biology, University of Leicester, Leicester
Hurley L.H.
Burley G.A.
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Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowLeicester Institute of Structural and Chemical Biology, Department of Molecular and Cell Biology, University of Leicester, Leicester
Burley G.A.
Branlant C.
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IMoPA (Ingénierie Moléculaire et Physiopathologie Articulaire), Centre National de la Recherche Scientifique (CNRNRS), Biopôle de l'Université de Lorraine, Vandoeuvre-lès-NancyLeicester Institute of Structural and Chemical Biology, Department of Molecular and Cell Biology, University of Leicester, Leicester
Branlant C.
Eperon I.C.
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Leicester Institute of Structural and Chemical Biology, Department of Molecular and Cell Biology, University of Leicester, LeicesterLeicester Institute of Structural and Chemical Biology, Department of Molecular and Cell Biology, University of Leicester, Leicester
Eperon I.C.
Dominguez C.
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Leicester Institute of Structural and Chemical Biology, Department of Molecular and Cell Biology, University of Leicester, LeicesterLeicester Institute of Structural and Chemical Biology, Department of Molecular and Cell Biology, University of Leicester, Leicester