X-ray micro-CT scanner for small animal imaging based on Timepix detector technology

被引：16

作者：

Dudak, Jan ^{[1
,2
]}

Zemlicka, Jan ^{[1
]}

Krejci, Frantisek ^{[1
]}

Polansky, Stepan ^{[1
]}

Jakubek, Jan ^{[1
]}

Mrzilkova, Jana ^{[3
]}

Patzelt, Matej ^{[3
]}

Trnka, Jan ^{[3
]}

机构：

[1] Czech Tech Univ, Inst Expt & Appl Phys, Prague 12800 2, Czech Republic

[2] Czech Tech Univ, Fac Biomed Engn, Kladno 27200, Czech Republic

[3] Charles Univ Prague, Fac Med 3, Prague 10000, Czech Republic

来源：

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | 2015年 / 773卷

关键词：

Computerized tomography; Hybrid detector; Timepix; Small animal imaging; COMPUTED TOMOGRAPHY; MICROTOMOGRAPHY; RESOLUTION;

D O I：

10.1016/j.nima.2014.10.076

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

We describe a newly developed compact micro-CT scanner with rotating gantry equipped with a Timepix Quad hybrid pixel semiconductor detector and a micro-focus X-ray tube providing spatial resolution down to 30 mu m. The resolving power of the device in relation to soft tissue sensitivity is demonstrated using a tissue-equivalent phantom and different types of biological samples. The results demonstrate that the use of noiseless particle counting detectors is a promising way to achieve sufficient soft tissue contrast even without any contrast agents. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：81 / 86

页数：6

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