Catalytic asymmetric formation of β-sultams

被引:52
|
作者
Zajac, Marian [1 ]
Peters, Rene [1 ]
机构
[1] ETH, Organ Chem Lab, CH-8093 Zurich, Switzerland
关键词
D O I
10.1021/ol070644c
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
beta-Sultams, highly strained sulfonyl analogues of beta-lactams, were prepared enantio- and diastereoselectively by tertiary amine catalyzed [2 + 2] cycloaddition reactions. The title compounds are practical precursors of highly enantioenriched biologically interesting,- aminosulfonyl derivatives.
引用
收藏
页码:2007 / 2010
页数:4
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