Pulmonary toxicity associated with nitric oxide in term infants with severe respiratory failure

被引：28
|
作者：
Hallman, M
Bry, K
Turbow, R
Waffarn, F
Lappalainen, U
机构：
[1] Univ Oulu, Dept Pediat, SF-90220 Oulu, Finland
[2] Univ Calif Irvine, Irvine Med Ctr, Dept Pediat, Div Neonatal Med, Orange, CA 92668 USA
[3] Vanderbilt Univ, Dept Pediat, Div Neonatal Med, Nashville, TN USA
[4] Sierra Vista Reg Med Ctr, San Luis Obispo, CA USA
来源：
JOURNAL OF PEDIATRICS | 1998年 / 132卷 / 05期
关键词：
D O I：
10.1016/S0022-3476(98)70312-9
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
We prospectively analyzed airway specimens from 24 newborn infants. Inhaled nitric oxide (less than or equal to 20 ppm for 1 to 4 days to 12 infants) did not affect the concentrations of the lipid peroxidation product, the surface activity, or the cytokines (interleukin-l, granulocyte-macrophage colony-stimulating factor, interleukin-l receptor antagonist). Nitrotyrosine was detected after 10 days of life in the two infants requiring prolonged ventilation, suggesting toxicity of endogenous nitric oxide.
引用
收藏
页码：827 / 829
页数：3
相关论文
共 50 条
  • [31] Treatment with Inhaled Nitric Oxide (iNO) In Neonates with Respiratory Failure Associated with Pulmonary Hypertension (PH)
    M T Mazzucchelli
    E Domínguez
    C Cannizzaro
    P Bellani
    C Couceiro
    Pediatric Research, 1998, 44 (5) : 814 - 814
  • [32] Initial dosing of inhaled nitric oxide in infants with hypoxic respiratory failure
    Guthrie, SO
    Walsh, WF
    Auten, KJ
    Clark, RH
    PEDIATRIC RESEARCH, 2003, 53 (04) : 357A - 357A
  • [33] Initial dosing of inhaled nitric oxide in infants with hypoxic respiratory failure
    Guthrie S.O.
    Walsh W.F.
    Auten K.
    Clark R.H.
    Journal of Perinatology, 2004, 24 (5) : 290 - 294
  • [34] Nitric oxide for the treatment of preterm infants with severe RDS and pulmonary hypertension
    Dani, Carlo
    Corsini, Iuri
    Cangemi, Jessica
    Vangi, Venturella
    Pratesi, Simone
    PEDIATRIC PULMONOLOGY, 2017, 52 (11) : 1461 - 1468
  • [35] Inhaled Nitric Oxide for Preterm Infants Born Between 22 and 28 Gestational Weeks with Severe Respiratory Failure
    Kakuage, S.
    EUROPEAN JOURNAL OF PEDIATRICS, 2016, 175 (11) : 1750 - 1750
  • [36] Inhaled nitric oxide in infants >1500 g and <34 weeks gestation with severe respiratory failure
    Van Meurs, K. P.
    Hintz, S. R.
    Ehrenkranz, R. A.
    Lemons, J. A.
    Ball, M. B.
    Poole, W. K.
    Perritt, R.
    Das, A.
    Higgins, R. D.
    Stevenson, D. K.
    JOURNAL OF PERINATOLOGY, 2007, 27 (06) : 347 - 352
  • [37] Neurodevelopmental outcomes of premature infants with severe respiratory failure enrolled in a randomized controlled trial of inhaled nitric oxide
    Hintz, Susan R.
    Van Meurs, Krisa P.
    Perritt, R.
    Poole, W. Kenneth
    Das, Abhik
    Stevenson, David K.
    Ehrenkranz, Richard A.
    Lemons, James A.
    Vohr, Betty R.
    Heyne, Roy
    Childers, David O.
    Peralta-Carcelen, Myriam
    Dusick, Anna
    Johnson, Yvette R.
    Morris, Brenda
    Dillard, Robert
    Vaucher, Yvonne
    Steichen, Jean
    Adams-Chapman, Ira
    Konduri, Ganesh
    Myers, Gary J.
    De Ungria, Marissa
    Tyson, Jon E.
    Higgins, Rosemary D.
    JOURNAL OF PEDIATRICS, 2007, 151 (01): : 16 - 22
  • [38] Respiratory management strategy impacts the outcome of hypoxic respiratory failure (HRF) in term and near term infants treated with inhaled nitric oxide (iNO)
    Dudell, GG
    St John, ES
    PEDIATRIC RESEARCH, 2004, 55 (04) : 508A - 508A
  • [39] Neonatal listeriosis with severe respiratory failure responding to nitric oxide inhalation
    Ichiba, H
    Fujioka, H
    Saitoh, M
    Shintaku, H
    PEDIATRICS INTERNATIONAL, 2000, 42 (06) : 696 - 698
  • [40] Inhaled nitric oxide in very preterm infants with severe respiratory distress syndrome
    Dani, Carlo
    Bertini, Giovanna
    Pezzati, Marco
    Filippi, Luca
    Cecchi, Alessandra
    Rubaltelli, Firmino F.
    ACTA PAEDIATRICA, 2006, 95 (09) : 1116 - 1123
12345