Efficient One-Pot Synthesis of 6-Arylpyrrolo[3,2-d]pyrimidines from 6-Arylethynyl-5-nitropyrimidines

被引：3

作者：

Cikotiene, Inga ^{[1
]}

Pudziuvelyte, Erika ^{[1
]}

Brukstus, Algirdas ^{[1
]}

机构：

[1] Vilnius Univ, Dept Organ Chem, Fac Chem, LT-03225 Vilnius, Lithuania

来源：

SYNLETT | 2010年 / 07期

关键词：

pyrrolo[3,2-d]pyrimidines; 6-arylethynyl-5-nitropyrimidines; enamines; cyclization; PURINE NUCLEOSIDE PHOSPHORYLASE; THYMIDYLATE SYNTHASE; TERT-BUTYLAMINE; CYCLIZATION; INHIBITORS; HETEROCYCLES; POTASSIUM; 5-OXIDES; DESIGN; CESIUM;

D O I：

10.1055/s-0029-1219544

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly concise one-pot synthesis of 6-arylpyrrolo[3,2-d]pyrimidines via conjugative addition reaction of secondary amines to 6-arylethynyl-5-nitropyrimidines and subsequent reduction is described.

引用

页码：1107 / 1109

页数：3

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