Efficient One-Pot Synthesis of 6-Arylpyrrolo[3,2-d]pyrimidines from 6-Arylethynyl-5-nitropyrimidines

被引：3
|
作者：
Cikotiene, Inga [1 ]
Pudziuvelyte, Erika [1 ]
Brukstus, Algirdas [1 ]
机构：
[1] Vilnius Univ, Dept Organ Chem, Fac Chem, LT-03225 Vilnius, Lithuania
来源：
SYNLETT | 2010年 / 07期
关键词：
pyrrolo[3,2-d]pyrimidines; 6-arylethynyl-5-nitropyrimidines; enamines; cyclization; PURINE NUCLEOSIDE PHOSPHORYLASE; THYMIDYLATE SYNTHASE; TERT-BUTYLAMINE; CYCLIZATION; INHIBITORS; HETEROCYCLES; POTASSIUM; 5-OXIDES; DESIGN; CESIUM;
D O I：
10.1055/s-0029-1219544
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A highly concise one-pot synthesis of 6-arylpyrrolo[3,2-d]pyrimidines via conjugative addition reaction of secondary amines to 6-arylethynyl-5-nitropyrimidines and subsequent reduction is described.
引用
收藏
页码：1107 / 1109
页数：3
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