Synthesis of some 2-heteryl substituted indoles

被引：0
|
作者：
Dubey, P. K. [1 ]
Babu, Balaji [1 ]
机构：
[1] JNTU Coll Engn, Dept Chem, Hyderabad 500072, Andhra Pradesh, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2007年 / 16卷 / 04期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Refluxing indole-2-carbohydrazide 1 with CS2 in the presence of KOH in ethanol gave 5-(1H-indol-2-yl) - [1,3,4-oxadiazol-2-thiol] 2. Condensation of 2 with hydrazine hydrate in refluxing pyridine gave 2-(5-mercapto-4-amino-1,2,4-triazol-3-yl) indole 3. Treatment of 3 with alpha-haloketone gave hitherto unknown 3-(1H-indol-2-yl)-6-aryl/alkyl-7H- [1,2,4] triazole [3,4-b] [1,3,4] thiadiazines 4. Reaction of 3 with aldehydes in the presence of piperidine at room temp gave 5.
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页码：357 / 360
页数：4
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