Regioselection in 1,3-dipolar cycloadditions of 3-methylpyridine N-imide to aromatic carbonitriles.: Synthesis of 2-aryl-8-methyl[1,2,4]triazolo [1,5-a]pyridines

被引：0

作者：

Zhang, GL ^{[1
]}

Hu, YZ ^{[1
]}

机构：

[1] Zhejiang Univ, Coll Pharmaceut Sci, Dept Med Chem, Hangzhou 310031, Peoples R China

来源：

JOURNAL OF CHEMICAL RESEARCH | 2002年 / 11期

关键词：

1,3-dipolar cycloaddition; pyridine N-imides; fused 1,2,4-triazoles; fused pyridines;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1-Amino-3-methylpyridinium mesitylenesulfonate (3) reacts with aromatic nitriles in the presence of potassium hydroxide, undergoing 1,3-dipolar cycloaddition followed by elimination of H-2 to give 2-aryl-8-methyl[1,2,4]triazolo[1,5-a]pyridines as the major products, rather than the 6-methyl isomers.

引用

页码：560 / 561

页数：2

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