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One-pot, three-component Mannich-type reaction catalyzed by functionalized ionic liquid
被引:29
|作者:
Fang, Dong
[1
,2
]
Gong, Kai
[2
]
Zhang, Dai-zhen
[1
]
Liu, Zu-liang
[1
,2
]
机构:
[1] Jiangsu Prov Key Lab Coast Wetland Bioresource &, Yancheng 224002, Peoples R China
[2] Nanjing Univ Sci & Technol, Sch Chem Engn, Nanjing 210094, Peoples R China
来源:
关键词:
Mannich-type reaction;
Ionic liquid;
Catalyst;
One-pot reaction;
AROMATIC-ALDEHYDES;
ANILINES;
KETONES;
D O I:
10.1007/s00706-009-0182-y
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
A three-component Mannich-type reaction of aromatic aldehydes, aromatic amines, and ketones was catalyzed by a novel functionalized ionic liquid, 3-(N,N-dimethyldodecylammonium)propanesulfonic acid hydrogen sulfate ([DDPA][HSO4]) at room temperature to give various beta-amino carbonyl compounds in good yields. The catalyst could be reused at least six times without noticeably reducing catalytic activity.
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页码:1325 / 1329
页数:5
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