One-pot three-component Mannich reaction catalyzed by iodine under solvent-free conditions

被引：3
|
作者：
Li Gang [1 ]
Long Ruiling [2 ]
Yang Jiangli [1 ]
机构：
[1] Anyang Normal Univ, Coll Chem & Chem Engn, Anyang, Peoples R China
[2] Xinxiang Med Univ, Dept Life Sci & Technol, Xinxiang, Peoples R China
来源：
KINETICS AND CATALYSIS | 2011年 / 52卷 / 03期
关键词：
ALDEHYDES; KETONES;
D O I：
10.1134/S0023158411030062
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
One-pot three-component Mannich reactions of ketones with aromatic aldehydes and aromatic amines are effectively catalyzed by molecular iodine at room temperature under solvent-free conditions to afford the corresponding beta-amino carbonyl compounds with moderate to excellent yields. The method has the following advantages: no use of solvent, mild condition, high reaction speed and small quantity of catalyst.
引用
收藏
页码：397 / 400
页数：4
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