Novel steroids from the soft coral Nephthea chabrolii

被引:27
|
作者
Su, Jui-Hsin
Lin, Fang-Yee
Huang, Ho-Cheng
Dai, Chang-Feng
Wu, Yang-Chang
Hu, Wan-Ping
Hsu, Chi-Hsin
Sheu, Jyh-Horng [1 ]
机构
[1] Natl Sun Yat Sen Univ, Dept Marine Biotechnol & Resources, Kaohsiung 80424, Taiwan
[2] Cheng Shiu Univ, Dept Chem Engn, Kaohsiung 833, Taiwan
[3] Natl Taiwan Univ, Inst Oceanog, Taipei 112, Taiwan
[4] Kaohsiung Med Univ, Inst Nat Prod, Kaohsiung 80708, Taiwan
[5] Kaohsiung Med Univ, Fac Biotechnol, Kaohsiung 80708, Taiwan
[6] Natl Sun Yat Sen Univ, Asian Pacific Ocean Res Ctr, Kaohsiung 804, Taiwan
关键词
chabrolosteroids; spirosteroid; Nephthea chobrolii;
D O I
10.1016/j.tet.2006.10.082
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Three new metabolites including two new steroids, chabrolosteroids A and B (1 and 2), and a novel spirosteroid chabrolosteroid C (3), were isolated from the organic extract of a Taiwanese soft coral Nephthea chabrolii. The structures of these metabolites were elucidated by extensive spectroscopic analysis and by comparison of the spectral data with those of related steroids. This is the first report of a steroid with a spiro-ring A, B system in natural products. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码:703 / 707
页数:5
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