Novel steroids from the soft coral Nephthea chabrolii

被引:27
|
作者
Su, Jui-Hsin
Lin, Fang-Yee
Huang, Ho-Cheng
Dai, Chang-Feng
Wu, Yang-Chang
Hu, Wan-Ping
Hsu, Chi-Hsin
Sheu, Jyh-Horng [1 ]
机构
[1] Natl Sun Yat Sen Univ, Dept Marine Biotechnol & Resources, Kaohsiung 80424, Taiwan
[2] Cheng Shiu Univ, Dept Chem Engn, Kaohsiung 833, Taiwan
[3] Natl Taiwan Univ, Inst Oceanog, Taipei 112, Taiwan
[4] Kaohsiung Med Univ, Inst Nat Prod, Kaohsiung 80708, Taiwan
[5] Kaohsiung Med Univ, Fac Biotechnol, Kaohsiung 80708, Taiwan
[6] Natl Sun Yat Sen Univ, Asian Pacific Ocean Res Ctr, Kaohsiung 804, Taiwan
关键词
chabrolosteroids; spirosteroid; Nephthea chobrolii;
D O I
10.1016/j.tet.2006.10.082
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Three new metabolites including two new steroids, chabrolosteroids A and B (1 and 2), and a novel spirosteroid chabrolosteroid C (3), were isolated from the organic extract of a Taiwanese soft coral Nephthea chabrolii. The structures of these metabolites were elucidated by extensive spectroscopic analysis and by comparison of the spectral data with those of related steroids. This is the first report of a steroid with a spiro-ring A, B system in natural products. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码:703 / 707
页数:5
相关论文
共 50 条
  • [21] New norsesquiterpene and sesquiterpene from a soft coral of the genus Nephthea
    Yang, Ruo-Lin
    Kuang, Yun-Yan
    Su, Jing-Yu
    Zeng, Long-Mei
    NATURAL PRODUCT RESEARCH, 2008, 22 (18) : 1605 - 1609
  • [22] New 4-methylated and 19-oxygenated steroids from the Formosan soft coral Nephthea erecta
    Cheng, Shi-Yie
    Dai, Chang-Feng
    Duh, Chang-Yih
    STEROIDS, 2007, 72 (08) : 653 - 659
  • [23] Prenylbicyclogermacrane diterpenoids from the formosan soft coral Nephthea pacifica
    El-Gamal, AAH
    Wang, SK
    Dai, CF
    Chen, IG
    Duh, CY
    JOURNAL OF NATURAL PRODUCTS, 2005, 68 (01): : 74 - 77
  • [24] A New Norsesquiterpenoid from a Bornean Soft Coral Genus Nephthea
    Ishii, Takahiro
    Matsuura, Hiroshi
    Zhan Zhaoqi
    Vairappan, Charles Santhanaraju
    MOLECULES, 2009, 14 (11) : 4591 - 4596
  • [25] New anti-inflammatory 4-methylated steroids from the Formosan soft coral Nephthea chabroli
    Huang, Ya-Ching
    Wen, Zhi-Hong
    Wang, Shang-Kwei
    Hsu, Chi-Hsin
    Duh, Chang-Yih
    STEROIDS, 2008, 73 (11) : 1181 - 1186
  • [26] New 19-oxygenated and 4-methylated steroids from the Formosan soft coral Nephthea chabroli
    Cheng, Shi-Yie
    Huang, Ya-Chiang
    Wen, Zhi-Hong
    Hsu, Chi-Hsin
    Wang, Shang-Kwei
    Dai, Chang-Feng
    Duh, Chang-Yih
    STEROIDS, 2009, 74 (06) : 543 - 547
  • [27] Two new constituents from the soft coral Nephthea hainansis
    Li, GQ
    Li, X
    Deng, ZW
    Guan, HS
    Lin, WH
    CHINESE CHEMICAL LETTERS, 2005, 16 (04) : 494 - 496
  • [28] Nardosinane sesquiterpenoids from the formosan soft coral Nephthea elongata
    Wang, Shang-Kwei
    Duh, Chang-Yih
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2007, 55 (05) : 762 - 765
  • [29] Four new sesquiterpenoids from the soft coral Nephthea chabrollii
    Rao, MR
    Sridevi, KV
    Venkatesham, U
    Rao, TP
    Lee, SS
    Venkateswarlu, Y
    JOURNAL OF CHEMICAL RESEARCH, 2000, (05) : 245 - 247
  • [30] Prenylbicyclogermacrane diterpenoids from the Formosan soft coral Nephthea elongata
    El-Gamal, Ali Ali Hassan
    Wang, Shang-Kwei
    Duh, Chang-Yih
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2007, 55 (06) : 890 - 893