Synthesis of the 3,5,3′,5′-3H4-2,2′-diphenylene-iodonium cation and of its 4-nitro derivative

The 3,5,3',5'-H-3(4)-2,2'-diphenyleneiodonium cation [H-3]-1 was synthesized in three steps from cold 2,2' -diaminodiphenyl. The nitration of [H-3]-1 gave easily the 4-nitro derivative [H-3]-2 These two compounds which contain four tritium labels were obtained with a high specific activity, and are proposed as tools to study the interaction of 2,2'-diphenyleneiodonium cations with redox enzymes, especially flavoproteins.