Facile synthesis of new oxalate dimers of naturally occurring 3-hydroxysteroids

被引：7
|
作者：
Nahar, L.
Sarker, S. D.
Turner, A. B.
机构：
[1] Univ Aberdeen, Dept Chem, Japp Lab, Aberdeen AB24 3UE, Scotland
[2] Univ Ulster, Sch Biomed Sci, Coleraine BT52 1SA, Londonderry, North Ireland
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2006年 / 42卷 / 05期
基金：
英国工程与自然科学研究理事会;
关键词：
steroid; oxalyl chloride; esterification; oxalate dimers; NMR;
D O I：
10.1007/s10600-006-0211-6
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Several symmetrical steroidal oxalate dimers were synthesised from naturally occurring 3-hydroxysteroids, namely, estrone (1), DHEA (3), pregnenolone (5), cholesterol (7), 5D-cholestane (9), and stigmasterol (11), using oxalyl chloride. Full spectroscopic data for all the new compounds are presented.
引用
收藏
页码：549 / 552
页数：4
相关论文
共 50 条
  • [1] Facile synthesis of new oxalate dimers of naturally occurring 3-hydroxysteroids
    L. Nahar
    S. D. Sarker
    A. B. Turner
    Chemistry of Natural Compounds, 2006, 42 : 549 - 552
  • [2] Synthesis of 17β-hydroxy steroidal oxalate dimers from naturally occurring steroids
    Nahar, Lutfun
    Sarker, Satyajit D.
    Turner, Alan B.
    ACTA CHIMICA SLOVENICA, 2007, 54 (04) : 903 - 906
  • [3] A facile synthesis of naturally occurring aminopeptidase inhibitor tyromycin A
    Mangaleswaran, S
    Argade, NP
    JOURNAL OF ORGANIC CHEMISTRY, 2001, 66 (15): : 5259 - 5261
  • [4] A facile synthesis of naturally occurring 5-(3-indolyl)oxazoles
    Kumar, Dalip
    Sundaree, Swapna
    Patel, Gautam
    Rao, V. S.
    TETRAHEDRON LETTERS, 2008, 49 (05) : 867 - 869
  • [5] Convenient synthesis of new pregnenolone oximinyl oxalate dimers
    L. Nahar
    S. D. Sarker
    A. B. Turner
    Chemistry of Natural Compounds, 2008, 44 : 315 - 318
  • [6] CONVENIENT SYNTHESIS OF NEW PREGNENOLONE OXIMINYL OXALATE DIMERS
    Nahar, L.
    Sarker, S. D.
    Turner, A. B.
    CHEMISTRY OF NATURAL COMPOUNDS, 2008, 44 (03) : 315 - 318
  • [7] FACILE SYNTHESIS OF BASIC SKELETONS OF NATURALLY-OCCURRING LACTONIC TERPENES
    KAMETANI, T
    HONDA, T
    MATSUMOTO, H
    FUKUMOTO, K
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1981, (05): : 1383 - 1385
  • [8] Facile Synthesis and Antibacterial Activity of Naturally Occurring 5-Methoxyfuroflavone
    Alam, Mohammad Sayed
    Lee, Dong-Ung
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2010, 58 (12) : 1643 - 1645
  • [9] Facile and Efficient Synthesis of Naturally Occurring Carbasugars (+)-Pericosines A and C+
    Usami, Yoshihide
    Ohsugi, Marie
    Mizuki, Koji
    Ichikawa, Hayato
    Arimoto, Masao
    ORGANIC LETTERS, 2009, 11 (12) : 2699 - 2701
  • [10] SYNTHESIS OF 3 NATURALLY-OCCURRING DIISPROPYLMETHYLPHENOLS
    RAMANAMMA, CV
    DINGE, AS
    PAKNIKAR, SK
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1989, 28 (06): : 517 - 519
12345