Facile synthesis of new oxalate dimers of naturally occurring 3-hydroxysteroids

被引：7
|
作者：
Nahar, L.
Sarker, S. D.
Turner, A. B.
机构：
[1] Univ Aberdeen, Dept Chem, Japp Lab, Aberdeen AB24 3UE, Scotland
[2] Univ Ulster, Sch Biomed Sci, Coleraine BT52 1SA, Londonderry, North Ireland
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2006年 / 42卷 / 05期
基金：
英国工程与自然科学研究理事会;
关键词：
steroid; oxalyl chloride; esterification; oxalate dimers; NMR;
D O I：
10.1007/s10600-006-0211-6
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Several symmetrical steroidal oxalate dimers were synthesised from naturally occurring 3-hydroxysteroids, namely, estrone (1), DHEA (3), pregnenolone (5), cholesterol (7), 5D-cholestane (9), and stigmasterol (11), using oxalyl chloride. Full spectroscopic data for all the new compounds are presented.
引用
收藏
页码：549 / 552
页数：4
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