Facile synthesis of new oxalate dimers of naturally occurring 3-hydroxysteroids

被引：7
|
作者：
Nahar, L.
Sarker, S. D.
Turner, A. B.
机构：
[1] Univ Aberdeen, Dept Chem, Japp Lab, Aberdeen AB24 3UE, Scotland
[2] Univ Ulster, Sch Biomed Sci, Coleraine BT52 1SA, Londonderry, North Ireland
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2006年 / 42卷 / 05期
基金：
英国工程与自然科学研究理事会;
关键词：
steroid; oxalyl chloride; esterification; oxalate dimers; NMR;
D O I：
10.1007/s10600-006-0211-6
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Several symmetrical steroidal oxalate dimers were synthesised from naturally occurring 3-hydroxysteroids, namely, estrone (1), DHEA (3), pregnenolone (5), cholesterol (7), 5D-cholestane (9), and stigmasterol (11), using oxalyl chloride. Full spectroscopic data for all the new compounds are presented.
引用
收藏
页码：549 / 552
页数：4
相关论文
共 50 条
  • [31] A NEW SYNTHESIS OF A NATURALLY-OCCURRING ISOCOUMARIN - 3,4-DIMETHYL-8-HYDROXYISOCOUMARIN (OOSPOLACTONE)
    SINGH, HN
    SINGH, RP
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1988, 65 (10) : 685 - 687
  • [32] Facile Enzymatic Synthesis of Diverse Naturally-Occurring β-D-Mannopyranosides Catalyzed by Glycoside Phosphorylases
    Liu, Jing
    Yin, Xuefei
    Li, Zitao
    Wu, Xiaocong
    Zheng, Zhaoxuan
    Fang, Junqiang
    Gu, Guofeng
    Wang, Peng G.
    Liu, Xianwei
    ACS CATALYSIS, 2021, 11 (05): : 2763 - 2768
  • [33] A FACILE SYNTHESIS OF 2 THIOACROLEIN DIMERS - A NEW ENTRY TO A FLAVOR COMPONENT IN ASPARAGUS
    BESLIN, P
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1983, 20 (06) : 1753 - 1754
  • [34] A NEW ROUTE FOR THE EFFICIENT SYNTHESIS OF (+/-)OCHROMYCINONE, A NATURALLY-OCCURRING BENZ[A]ANTHRAQUINONE
    GUINGANT, A
    BARRETO, MM
    TETRAHEDRON LETTERS, 1987, 28 (27) : 3107 - 3110
  • [35] SYNTHESIS OF AZANZONE-A, A NEW NATURALLY-OCCURRING O-NAPHTHOQUINONE
    LETCHER, RM
    WONG, MC
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1992, (22): : 3035 - 3037
  • [36] A NEW SYNTHESIS OF THE NATURALLY-OCCURRING FREE-RADICAL SCAVENGER CARAZOSTATIN
    SHIN, K
    OGASAWARA, K
    CHEMISTRY LETTERS, 1995, (04) : 289 - 290
  • [37] SYNTHESIS OF A NEW NATURALLY-OCCURRING 3-PHENYL-4H-1-BENZOPYRAN-4-ONE
    PARMAR, VS
    SINGH, S
    JAIN, R
    SYNTHETIC COMMUNICATIONS, 1988, 18 (05) : 511 - 517
  • [38] SYNTHESIS OF NATURALLY-OCCURRING PARA-HYDROXYACETOPHENONE DERIVATIVES .3.
    BOHLMANN, F
    STOHR, FM
    LIEBIGS ANNALEN DER CHEMIE, 1980, (02): : 185 - 191
  • [39] A Novel and Short Synthesis of Naturally Occurring 5-(3′-Indolyl)oxazoles
    Kumar, Dalip
    Sundaree, Swapna
    Patel, Gautam
    Kumar, Anil
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2010, 47 (06) : 1425 - 1428
  • [40] NATURALLY OCCURRING ACETYLENES .3. SYNTHESIS OF (+L-)-HELENYNOLIC ACID
    PATRICK, TB
    MELM, GF
    JOURNAL OF ORGANIC CHEMISTRY, 1979, 44 (04): : 645 - 646
12345