SYNTHESIS AND CHARACTERIZATION OF NOVEL PYRIMIDINE DERIVATIVES FROM 2,3-FURANDIONES

被引:4
|
作者
Koca, Irfan [1 ]
Yildirim, Ismail [2 ]
机构
[1] Bozok Univ, Fac Arts & Sci, Dept Chem, TR-66200 Yozgat, Turkey
[2] Erciyes Univ, Fac Arts & Sci, Dept Chem, TR-38039 Kayseri, Turkey
关键词
2,3-Furandione; pyrimidine-2(1H)-one; pyrimidine-2(1-H)-thione; nucleophilic cycloaddition; FUNCTIONALIZED; 1H-PYRIMIDINES; OXALYL COMPOUNDS; ENAMINONES; INHIBITORS; AGENTS; ACID;
D O I
10.1515/HC.2009.15.5.377
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Various novel pyrimidine-2(1H)-one and pyrimidine-2(1H)-thione derivatives 3a-m have been synthesized efficiently in good yields by the treatment of 4-p-methylbenzoyl-5-p-methylphenyl-2,3-furandione (1a) and 4-(3,4-dimethoxybenzoyl)-5-(3,4-dimethoxyphenyl)-2,3-furandione (1b) with some ureas and thioureas 2. Structures of these compounds 3 were established on the basis of elemental analysis, IR, H-1- and C-13-NMR spectral studies.
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页码:377 / 384
页数:8
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