Developing a contact probe for rodent fundus imaging in a confocal scanning laser ophthalmoscope

被引：4

作者：

Jiang, Xiaoyun ^{[1
]}

Ding, Yichen ^{[1
]}

Wang, Wenyao ^{[2
]}

Huang, Zhiyu ^{[1
]}

Wang, Zhiru ^{[3
,4
]}

Anginieur, Elie de Lestrange ^{[1
]}

Yu, Yue ^{[1
]}

Li, Jun ^{[3
]}

Pu, Mingliang ^{[2
]}

Ren, Qiushi ^{[1
]}

Li, Changhui ^{[1
]}

机构：

[1] Peking Univ, Dept Biomed Engn, Beijing 100871, Peoples R China

[2] Peking Univ, Sch Basic Med Sci, Dept Anat, Beijing 100191, Peoples R China

[3] Peking Univ, Lab Anim Ctr, Beijing 100871, Peoples R China

[4] Jilin Univ, Sch Publ Hlth, Changchun 130012, Peoples R China

来源：

CHINESE OPTICS LETTERS | 2016年 / 14卷 / 03期

基金：

美国国家科学基金会; 国家教育部博士点专项基金资助;

关键词：

SCHEMATIC EYE; MOUSE MODEL; RAT EYE; RETINA; OPTICS; ABERRATIONS; RESOLUTION; PATHWAY;

D O I：

10.3788/COL201614.031701

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Since significant ocular differences in both anatomical structure and optical properties exist between rodents and humans, clinical imaging devices for human use are not suitable for use on rodents. In this study, we develop a contact probe with a flexible surface that can closely fit the rodent cornea for fundus imaging with a confocal scanning laser ophthalmoscope. Both Zemax simulation and in vivo fundus imaging demonstrate that this contact probe can significantly improve both the imaging quality and the operational convenience.

引用

页数：4

共 50 条

[1] Developing a contact probe for rodent fundus imaging in a confocal scanning laser ophthalmoscope
江晓芸
丁翼晨
王文耀
黄智宇
王志茹
Elie de Lestrange Anginieur
俞玥
李军
濮鸣亮
任秋实
李长辉
[J]. Chinese Optics Letters, 2016, 14 (03) : 80 - 83
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[10] Altered fundus appearance resulting from autofluorescence imaging with the confocal scanning laser ophthalmoscope (cSLO) in cats
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[J]. VETERINARY OPHTHALMOLOGY, 2014, 17 (05) : 385 - 388

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