A one-pot synthesis of imidazo[1,5-a]pyridines

被引：64
|
作者：
Crawforth, James M. [1 ]
Paoletti, Melissa [2 ]
机构：
[1] Pfizer Global Res & Dev, Sandwich CT13 9NJ, Kent, England
[2] Univ Camerino, Dept Chem Sci, I-162032 Camerino, MC, Italy
来源：
TETRAHEDRON LETTERS | 2009年 / 50卷 / 34期
关键词：
REAGENT;
D O I：
10.1016/j.tetlet.2009.06.061
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A one-pot synthesis of imidazo[1,5-a]pyridines starting from a carboxylic acid and 2-methylaminopyridines allowing introduction of various substituents at the 1- and 3-positions is achieved using propane phosphoric acid anhydride in ethyl or n-butyl acetate at reflux. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：4916 / 4918
页数：3
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