Ammonium chloride catalyzed one-pot synthesis of imidazo[1,2-a]pyridines

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作者
Ahmad Shaabani
Fahimeh Rezazadeh
Ebrahim Soleimani
机构
[1] Shahid Beheshti University,Department of Chemistry
关键词
Imidazo[1,2-; ]pyridine; Ammonium chloride; Three-component reaction; Isocyanide.;
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摘要
Ammonium chloride as a very inexpensive and readily available reagent efficiently catalyzes one-pot, three-component Groebke condensation reactions of aldehydes, isocyanides, and 2-aminopyridines or 2-aminopyrimidines in methanol to afford the corresponding imidazo[1,2-a]pyridines in high yields at room temperature.
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页码:931 / 933
页数:2
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