Iodine-Mediated One-Pot Synthesis of Imidazo[1,5-a]Pyridines

被引：0
|
作者：
Huang, Lang [1 ]
Liu, Yarong [1 ]
Guan, Zhipeng [1 ,2 ]
Dong, Zhibing [1 ,2 ,3 ]
机构：
[1] Wuhan Inst Technol, Sch Chem & Environm Engn, Wuhan 430205, Peoples R China
[2] Hubei Three Gorges Lab, Yichang 443000, Peoples R China
[3] Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453007, Peoples R China
来源：
CATALYSTS | 2024年 / 14卷 / 09期
基金：
中国国家自然科学基金;
关键词：
2-aminomethylpyridine; benzaldehyde; cyclization; sodium benzenesulfinate; iodine; IMIDAZOPYRIDINES; DERIVATIVES; IMIDAZO; MONO;
D O I：
10.3390/catal14090601
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
In this report, we developed an efficient one-pot method for the synthesis of 3-phenyl-1-(phenylthio)imidazo[1,5-a]pyridine analogs starting from 2-aminomethylpyridines, benzaldehydes, and sodium benzenesulfinates, which constructed C-N and C-S bonds simultaneously. The method features mild reaction conditions, a wide range of substrates, high atom utilization, and convenient and easily accessible starting materials.
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页数：11
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