Violapyrones A-G, α-Pyrone Derivatives from Streptomyces violascens Isolated from Hylobates hoolock Feces

被引：51
|
作者：
Zhang, Jiaoyue [1 ]
Jiang, Yi [2 ]
Cao, Yanru [2 ]
Liu, Jiang [3 ]
Zheng, Dan [1 ]
Chen, Xiu [2 ]
Han, Li [3 ]
Jiang, Chenglin [2 ,3 ]
Huang, Xueshi [1 ]
机构：
[1] China Med Univ, Lab Metab Dis Res & Drug Dev, Shenyang 110001, Peoples R China
[2] Yunnan Univ, Yunnan Inst Microbiol, Kunming 650091, Peoples R China
[3] Northeastern Univ, Coll Life & Hlth Sci, Inst Microbial Pharmaceut, Shenyang 110819, Peoples R China
来源：
JOURNAL OF NATURAL PRODUCTS | 2013年 / 76卷 / 11期
基金：
中国国家自然科学基金;
关键词：
ANTIBIOTICS; METABOLITES; GUT;
D O I：
10.1021/np4003417
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Seven new 3,4,6-trisubstituted alpha-pyrone derivatives, violapyrones A-G (1-7), were isolated from Streptomyces violascens obtained from Hylobates hoolock feces. Their structures were elucidated on the basis of detailed spectroscopic analysis. The antimicrobial activities of 1-7 were evaluated against Gram-positive and Gram-negative bacteria and against fungi. Compounds 1-3 showed moderate antibacterial activities against Bacillus subtilis and Staphylococcus aureus with MIC values of 4-32 mu g/mL.
引用
收藏
页码：2126 / 2130
页数：5
相关论文
共 50 条
  • [21] INSECTICIDAL ACTIVITY OF PYRROLIZINE DERIVATIVES ISOLATED FROM STREPTOMYCES-GRISEUS
    JIZBA, J
    SAMOUKINA, GV
    IVANOVAKOVACHEVA, T
    KANDYBIN, NV
    FOLIA MICROBIOLOGICA, 1992, 37 (06) : 461 - 462
  • [22] α-pyrone derivatives from the endophytic Fusarium sp. L33 isolated from Dioscorea opposita
    Tian, Ruo-Dan
    Sheng, Meng-Ke
    Zhao, Ying-Fei
    Wen, Chun-Nan
    Liu, Miao
    Ma, Ji
    PHYTOCHEMISTRY LETTERS, 2024, 62 : 14 - 17
  • [23] New anti-inflammatory metabolites produced by Streptomyces violaceoruber isolated from Equus burchelli feces
    Ma, Jian
    Lei, Hui
    Chen, Xiu
    Bi, Xiaoxu
    Jiang, Yi
    Han, Li
    Huang, Xueshi
    JOURNAL OF ANTIBIOTICS, 2017, 70 (10): : 991 - 994
  • [24] α-Pyrone Polyketides from Streptomyces ambofaciens BI0048, an Endophytic Actinobacterial Strain Isolated from the Red Alga Laurencia glandulifera
    Rab, Eniko
    Kekos, Dimitrios
    Roussis, Vassilios
    Ioannou, Efstathia
    MARINE DRUGS, 2017, 15 (12):
  • [25] Antiviral properties of extracts of Streptomyces sp. SMU 03 isolated from the feces of Elephas maximus
    Li, Fangfang
    Lu, Shengsheng
    Xie, Xi
    Fan, Sheng
    Chen, Daiwei
    Wu, Shaohua
    He, Jian
    FITOTERAPIA, 2020, 143
  • [26] Albusamides A-G: Hydroxylated Fatty Amine Derivatives from the Deep-Sea-Derived Actinomycete Streptomyces albus 228DD-066 and Their Cytotoxic Activity
    Shin, Hee Jae
    Jung, Su-Yeon
    Kang, Jong Soon
    Heo, Chang-Su
    Park, Sun Joo
    JOURNAL OF NATURAL PRODUCTS, 2024, 87 (10): : 2432 - 2440
  • [27] New anti-inflammatory metabolites produced by Streptomyces violaceoruber isolated from Equus burchelli feces
    Jian Ma
    Hui Lei
    Xiu Chen
    Xiaoxu Bi
    Yi Jiang
    Li Han
    Xueshi Huang
    The Journal of Antibiotics, 2017, 70 : 991 - 994
  • [28] New anti-influenza A viral norsesquiterpenoids isolated from feces-residing Streptomyces sp
    Lu, Shengsheng
    Xie, Xi
    Hu, Jianan
    Lin, Haixing
    Li, Fangfang
    Zhou, Runhong
    Guo, Jiayin
    Wu, Shaohua
    He, Jian
    FITOTERAPIA, 2022, 157
  • [29] Eutyscoparols A-G, polyketide derivatives from endophytic fungus Eutypella scoparia SCBG-8
    Zhang, Wenge
    Wang, Miaomiao
    Zhang, Sha
    Xu, Kangping
    Tan, Guishan
    Qiu, Shengxiang
    Zou, Zhenxing
    Tan, Haibo
    FITOTERAPIA, 2020, 146
  • [30] Secondary Metabolites with Cytotoxic Activities from Streptomyces sp. BM-8 Isolated from the Feces of Equus quagga
    Lu, Shengsheng
    Hu, Jianan
    Xie, Xi
    Zhou, Runhong
    Li, Fangfang
    Huang, Ruifeng
    He, Jian
    MOLECULES, 2021, 26 (24):
12345