Computation of residence time in the simulation of pulsatile ventricular assist devices

被引：80
|
作者：
Long, C. C. [2 ]
Esmaily-Moghadam, M. [2 ]
Marsden, A. L. [2 ]
Bazilevs, Y. [1 ]
机构：
[1] Univ Calif San Diego, Dept Struct Engn, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Dept Mech & Aerosp Engn, La Jolla, CA 92093 USA
来源：
COMPUTATIONAL MECHANICS | 2014年 / 54卷 / 04期
关键词：
PVAD; Residence time; FSI; Isogeometric analysis; Biomechanics; FEM; Blood flow; FLUID-STRUCTURE INTERACTION; FINITE-ELEMENT COMPUTATION; DERIVATIVE-FREE OPTIMIZATION; STAGNATION POINT FLOW; PLATELET DEPOSITION; CONSTRAINED OPTIMIZATION; ISOGEOMETRIC ANALYSIS; BLOOD-FLOW; FORMULATION; ALGORITHMS;
D O I：
10.1007/s00466-013-0931-y
中图分类号：
O1 [数学];
学科分类号：
0701 ; 070101 ;
摘要：
A continuum-based model of particle residence time for moving-domain fluid mechanics and fluid-structure interaction (FSI) computations is proposed, analyzed, and applied to the simulation of an adult pulsatile ventricular assist device (PVAD). Residence time is a quantity of clinical interest for blood pumps because it correlates with thrombotic risk. The proposed technique may be easily implemented in any flow or FSI solver. In the context of PVADs the results of the model may be used to assess how efficiently the pump moves the blood through its interior. Three scalar measures of particle residence time are also proposed. These scalar quantities may be used in the PVAD design with the goal of reducing thrombotic risk.
引用
收藏
页码：911 / 919
页数：9
相关论文
共 50 条
  • [31] Evaluating piezoelectric hydraulic pumps as drivers for pulsatile pediatric ventricular assist devices
    Valdovinos, John
    Williams, Ryan J.
    Levi, Daniel S.
    Carman, Gregory P.
    [J]. JOURNAL OF INTELLIGENT MATERIAL SYSTEMS AND STRUCTURES, 2014, 25 (10) : 1276 - 1285
  • [32] Echocardiographic differences in mass and volume among patients with pulsatile and non-pulsatile left ventricular assist devices
    Thohan, V
    Nagueh, SF
    Stetson, SJ
    Koerner, MM
    Noon, GP
    Loebe, M
    Torre-Amione, G
    [J]. CIRCULATION, 2001, 104 (17) : 430 - 430
  • [33] In vitro characterization of aortic retrograde and antegrade flow from pulsatile and non-pulsatile ventricular assist devices
    DiGiorgi, PL
    Smith, DL
    Naka, Y
    Oz, MC
    [J]. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2004, 23 (02): : 186 - 192
  • [34] Effects of pulsatile- and continuous-flow left ventricular assist devices on left ventricular unloading
    Garcia, Santiago
    Kandar, Forum
    Boyle, Andrew
    Colvin-Adams, Monica
    Lliao, Kenneth
    Joyce, Lyle
    John, Ranjit
    [J]. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2008, 27 (03): : 261 - 267
  • [35] Hemodynamic effects of pulsatile unloading of left ventricular assist devices (LVAD) on intraventricular flow and ventricular stress
    Gu, Kaiyun
    Guan, Zhiyuan
    Chang, Yu
    Gao, Bin
    Ling, Yunpeng
    Song, Zhiming
    Wan, Feng
    [J]. JOURNAL OF BIOMECHANICS, 2020, 103
  • [36] The incidence of right ventricular dysfunction is similar in pulsatile and continuous-flow left ventricular assist devices
    Feller, Erika D.
    Sorensen, Erik N.
    Johnson, Frances L.
    Gottlieb, Stephen S.
    Haddad, Michel
    Pierson, Richard N.
    Griffith, Bartley P.
    [J]. JOURNAL OF CARDIAC FAILURE, 2006, 12 (06) : S49 - S49
  • [37] Computer Simulation of the Blood Flow in a Planar Configuration for a Pulsatile Ventricular Assist Device
    Fries, E.
    Berli, M.
    Campana, D.
    Ubal, S.
    Di Paolo, J.
    [J]. VI LATIN AMERICAN CONGRESS ON BIOMEDICAL ENGINEERING (CLAIB 2014), 2014, 49 : 892 - 895
  • [38] Effect of pulsatile amd nonpulsatile left ventricular assist devices on plasma renin activity
    Welp, H.
    Etz, C.
    Tjan, T.
    Scheld, H. H.
    Schmid, C.
    [J]. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2005, 24 (02): : S58 - S58
  • [39] Shape optimization of pulsatile ventricular assist devices using FSI to minimize thrombotic risk
    C. C. Long
    A. L. Marsden
    Y. Bazilevs
    [J]. Computational Mechanics, 2014, 54 : 921 - 932
  • [40] Hemodynamic and exercise performance with Pulsatile and continuous-flow left ventricular assist devices
    Haft, Jonathan
    Armstrong, William
    Dyke, David B.
    Aaronson, Keith D.
    Koelling, Todd M.
    Farrar, David J.
    Pagani, Francis D.
    [J]. CIRCULATION, 2007, 116 (11) : I8 - I15
12345