A Metal-Free Approach to Carboxylic Acids by Oxidation of Alkyl, Aryl, or Heteroaryl Alkyl Ketones or Arylalkynes

被引：19

作者：

Kumar, K. A. Aravinda ^{[1
]}

Venkateswarlu, Vunnam ^{[1
,2
]}

Vishwakarma, Ram A. ^{[1
,2
]}

Sawant, Sanghapal D. ^{[1
,2
]}

机构：

[1] CSIR, Indian Inst Integrat Med, Div Med Chem, Jammu 180001, India

[2] Acad Sci & Innovat Res, New Delhi 110001, India

来源：

SYNTHESIS-STUTTGART | 2015年 / 47卷 / 20期

关键词：

ketones; alkynes; oxidation; carboxylic acids; green chemistry; POTASSIUM-PERMANGANATE OXIDATIONS; HYDROGEN-PEROXIDE; N-TRIFLUOROACYLATION; SELECTIVE OXIDATION; CATALYZED SYNTHESIS; OSMIUM TETRAOXIDE; STYRENE OXIDATION; ORGANIC-COMPOUNDS; ALLYLIC ALCOHOLS; ALPHA-DIKETONES;

D O I：

10.1055/s-0034-1381026

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The metal-free oxidation of dialkyl, alkyl aryl, or alkyl heteroaryl ketones or arylalkynes to the corresponding carboxylic acids is achieved using an oxidative mixture of Oxone and trifluoroacetic acid. This green method is a simple and mild protocol to obtain carboxylic derivatives in excellent yields.

引用

页码：3161 / 3168

页数：8

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