Synthesis of Indole Derivatives via Domino Reactions

被引:10
|
作者
Feng, Yadong [1 ]
Zhang, Hong [1 ]
Cheng, Guolin [1 ]
Cui, Xiuling [1 ]
机构
[1] Huaqiao Univ, Xiamen Key Lab Marine & Gene Drugs, Inst Mol Med, Engn Res Ctr Mol Med,Minist Educ, Xiamen 361021, Peoples R China
关键词
domino reactions; metal catalysis; indole derivatives; synthesis; CATALYZED SYNTHESIS; COUPLING REACTIONS; CYCLIZATION; CASCADE; ARYLATION; INSERTION; ANNULATION; CHEMISTRY; SEQUENCE; ANILINES;
D O I
10.6023/cjoc201403015
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Domino reactions have received great attentions of organic chemist as an efficient protocol to synthesize indole derivatives. In this process, it is not required isolating or purifying the intermediates, changing the reaction condition and adding reagents. Transition metal-catalyzed domino reactions to synthesize indole derivatives have already been widely studied and become a powerful tool. In this paper, the progress of recent domino reactions applied to construct indole and its derivatives is reviewed, focusing on the transition metal-catalyzed domino reactions, and detailed analysis on the versatility and applications.
引用
收藏
页码:1499 / 1508
页数:10
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