4,7-Dimethoxy-1,10-phenanthroline:: An excellent ligand for the Cu-catalyzed N-arylation of imidazoles

被引：268
|
作者：
Altman, Ryan A. [1 ]
Buchwald, Stephen L. [1 ]
机构：
[1] MIT, Dept Chem, Cambridge, MA 02139 USA
来源：
ORGANIC LETTERS | 2006年 / 8卷 / 13期
关键词：
D O I：
10.1021/ol0608505
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
4,7-Dimethoxy-1,10-phenanthroline (L) was found to be an efficient ligand for the copper-catalyzed N-arylation of imidazole with aryl iodides and bromides under mild conditions. A variety of hindered and functionalized imidazoles and aryl halides were transformed in good to excellent yields.
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收藏
页码：2779 / 2782
页数：4
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