Notch activation drives resistance to Kras(G12C) inhibition in lung adenocarcinoma

被引：0
|
作者：
Hwang, Elizabeth E. [1 ]
Lee, Alex [1 ]
Leung, Stanley [1 ]
Breese, Marcus [1 ]
Sweet-Cordero, Alejandro [1 ]
机构：
[1] Univ Calif San Francisco, San Francisco, CA USA
来源：
CANCER RESEARCH | 2022年 / 82卷 / 12期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1107
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Targeting KRAS G12C with Covalent Inhibitors
    Ostrem, Jonathan M. L.
    Shokat, Kevan M.
    ANNUAL REVIEW OF CANCER BIOLOGY, 2022, 6 : 49 - 64
  • [42] Clinical Data for KRAS G12C Inhibitors
    Kim, H. R.
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (03) : S95 - S96
  • [43] The promise and peril of KRAS G12C inhibitors
    Moore, Amanda R.
    Malek, Shiva
    CANCER CELL, 2021, 39 (08) : 1059 - 1061
  • [44] Establishment of KRAS G12C mutant brain metastasis models for preclinical evaluation of KRAS G12C targeted anticancer therapy
    Chen, Qikuan
    Wang, Guilan
    Yin, Yingfei
    CANCER RESEARCH, 2024, 84 (06)
  • [45] Molecular Epidemiology of KRAS G12C Mutations in Chinese Lung Cancer Patients
    Loong, H.
    Du, N.
    Cheng, C.
    Lin, H.
    Guo, J.
    Lin, G.
    Li, M.
    Jiang, T.
    Shi, Z.
    Cui, Y.
    Jin, X.
    Yao, J.
    Xing, Y.
    Yao, M.
    Wang, K.
    Mok, T.
    Liu, L.
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (03) : S426 - S426
  • [46] KRAS G12C mutations in non-small cell lung cancer
    Li, J. J.
    Wu, X. J.
    Farzin, M.
    Bray, V.
    Williamson, J.
    Pal, A.
    Yip, P. Y.
    Hagelamin, A.
    Ding, P.
    Nindra, U.
    Vinod, S.
    French, B.
    Chua, W.
    Gupta, R.
    Cooper, W. A.
    Wang, B.
    Lee, C. S.
    HISTOPATHOLOGY, 2024, 85 : 25 - 25
  • [47] Suppression of mutant Kirsten-RAS (KRAS G12C) non-small cell lung cancer (NSCLC) resistance to KRAS G12C inhibitors by dual inhibition of hepatocyte growth factor receptor (MET) and V-ATPase
    Rosell, R.
    Gomez-Vazquez, J. L.
    Lewintre, E. Jantus
    Ito, M.
    Cao, P.
    Cai, X.
    Xing, B.
    Farinas, S. Calabuig
    Cardona, A. F.
    Rodriguez, J. K.
    Jordan, M. Marco
    Valdunciel, C. Pedraz
    Molina-Vila, M. A.
    Codony-Servat, J.
    Dantes, Z.
    Aguilar, A.
    Sullivan, I. G.
    Horno, I. Moya
    Cirera, L.
    Gonzalez-Cao, M.
    JOURNAL OF THORACIC ONCOLOGY, 2023, 18 (04) : S149 - S149
  • [48] The MET Inhibitor Tepotinib Potentially Inhibits KRAS G12C and SHOC2 in KRAS G12C Non-Small Cell Lung Cancer (NSCLC)
    Rosell, R.
    Jain, A.
    Codony-Servat, J.
    Shivamallu, C.
    Kollur, S. Prasad
    Prasad, A.
    Jantus-Lewintre, E.
    Ito, M.
    Cardona, A. F.
    Arrieta, O.
    Cao, P.
    Cai, X.
    Xing, B.
    Pedraz-Valdunciel, C.
    Dantes, Z.
    Sullivan, I.
    Aguilar, A.
    Molina-Vila, M. A.
    Gonzalez-Cao, M.
    JOURNAL OF THORACIC ONCOLOGY, 2023, 18 (11) : S112 - S112
  • [49] Aurora kinase A inhibition overcomes adaptive resistance to KRAS G12C inhibitor by G1-checkpoint induced apoptosis in KRAS non-small cell lung cancer
    Li, Chendi
    Chang, Jeremy
    Graser, Christopher J.
    Syed, Usman M.
    Nimbalkar, Anahita
    Shen, Yi
    Altschuler, Steve
    Wu, Lani
    Michor, Franziska
    Gong, Xueqian
    Hata, Aaron N.
    MOLECULAR CANCER THERAPEUTICS, 2023, 22 (12)
  • [50] Focal adhesive kinase inhibitor IN10018 sensitizes KRAS mutant cancer and overcomes drug resistance of KRAS G12C inhibition
    Zhang, Baoyuan
    Zhang, Yan
    Zhang, Jiangwei
    Liu, Ping
    Jiao, Bo
    Wang, Zaiqi
    Ren, Ruibao
    CANCER RESEARCH, 2020, 80 (16)
12345