Notch activation drives resistance to Kras(G12C) inhibition in lung adenocarcinoma

被引：0
|
作者：
Hwang, Elizabeth E. [1 ]
Lee, Alex [1 ]
Leung, Stanley [1 ]
Breese, Marcus [1 ]
Sweet-Cordero, Alejandro [1 ]
机构：
[1] Univ Calif San Francisco, San Francisco, CA USA
来源：
CANCER RESEARCH | 2022年 / 82卷 / 12期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1107
引用
收藏
页数：2
相关论文
共 50 条
  • [21] Synergism of KRAS G12C Inhibitor and mTOR Inhibitor in Lung Adenocarcinoma and Squamous Cell Carcinoma
    Ito, M.
    Miyata, Y.
    Hirano, S.
    Morihara, N.
    Irisuna, F.
    Takemoto, M.
    Tsutani, Y.
    Okada, M.
    JOURNAL OF THORACIC ONCOLOGY, 2023, 18 (11) : S429 - S429
  • [22] Prognostic value of KRAS G12C mutation in lung adenocarcinoma stratified by stages and radiological features
    Cao, Hang
    Ma, Zelin
    Li, Yuan
    Zhang, Yang
    Chen, Haiquan
    JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2023, 166 (06): : E479 - E499
  • [23] KRAS G12C lung adenocarcinoma represents a distinct group of patients with different response to immunotherapy
    Masfarre, L.
    Rocha, P.
    Clave, S.
    Moliner, L.
    Navarro-Gorro, N.
    Rios-Hoyo, A.
    Sanchez, I.
    Giner, M.
    Corbera, A.
    Taus, A.
    Bellosillo, B.
    Arriola, E.
    ANNALS OF ONCOLOGY, 2022, 33 : S109 - S109
  • [24] KRAS G12C inhibition with sotorasib in metastatic colorectal cancer
    Severi, Christophe
    Van Cutsem, Eric
    ANNALS OF PALLIATIVE MEDICINE, 2022, 11 (08) : 2792 - 2795
  • [25] Clinical and Molecular profiling of KRAS G12C lung adenocarcinomas
    Bulusu, Venkata
    Jessop, Susan
    Paul, Sherin
    Chapman, Timothy
    Ben-Gashir, Mohamed
    Geetha, Anil
    Punnen, Geethu
    Aslam, Shahzeena
    Hutka, Margaret
    LUNG CANCER, 2023, 178 : S18 - S18
  • [26] KRAS G12C Mutations in NSCLC: From Target to Resistance
    Addeo, Alfredo
    Banna, Giuseppe Luigi
    Friedlaender, Alex
    CANCERS, 2021, 13 (11)
  • [27] The Use of Lung Adenocarcinoma Patient-Derived Xenografts and Organoids to Study GDP-KRAS G12C Inhibitor Resistance
    Rosen, J.
    Sacher, A.
    Pham, N. -A.
    Weiss, J.
    Li, Q.
    Koga, T.
    Tucker, S.
    Radulovich, N.
    Koers, A.
    Niedbala, M.
    Ross, S.
    Tsao, M. -S.
    JOURNAL OF THORACIC ONCOLOGY, 2022, 17 (09) : S437 - S438
  • [28] KRAS G12C mutation and risk of disease recurrence in stage I surgically resected lung adenocarcinoma
    Gallina, F. T.
    Marinelli, D.
    Melis, E.
    Forcella, D.
    Taje, R.
    Buglioni, S.
    Visca, P.
    Torchia, A.
    Cecere, F. L.
    Botticelli, A.
    Santini, D.
    Ciliberto, G.
    Cappuzzo, F.
    Facciolo, F.
    LUNG CANCER, 2023, 181
  • [29] KRAS G12C mutation and risk of disease recurrence in stage I surgically resected lung adenocarcinoma
    Marinelli, D.
    Melis, E.
    Torchia, A.
    Forcella, D.
    Botticelli, A.
    Visca, P.
    Buglioni, S.
    Facciolo, F.
    Gallina, F. T.
    JOURNAL OF THORACIC ONCOLOGY, 2023, 18 (04) : S91 - S92
  • [30] Aurora A kinase inhibition with VIC-1911 overcomes intrinsic and acquired resistance to KRASG12C inhibition in KRAS(G12C)-mutated lung cancer
    Lee, Jong Woo
    Kim, Sundong
    Yang, Cindy
    Burtness, Barbara
    MOLECULAR CANCER THERAPEUTICS, 2021, 20 (12)
12345