An efficient continuous flow process for the synthesis of a non-conventional mixture of fructooligosaccharides

被引：34

作者：

Zambelli, Paolo ^{[1
]}

Tamborini, Lucia ^{[2
]}

Cazzamalli, Samuele ^{[2
]}

Pinto, Andrea ^{[2
]}

Arioli, Stefania ^{[1
]}

Balzaretti, Silvia ^{[1
]}

Plou, Francisco J. ^{[3
]}

Fernandez-Arrojo, Lucia ^{[3
]}

Molinari, Francesco ^{[1
]}

Conti, Paola ^{[2
]}

Romano, Diego ^{[1
]}

机构：

[1] Univ Milan, Dept Food Environm & Nutr Sci DeFENS, I-20133 Milan, Italy

[2] Univ Milan, Dept Pharmaceut Sci DISFARM, I-20133 Milan, Italy

[3] CSIC, Inst Catalisis & Petr Quim, Madrid 28049, Spain

来源：

FOOD CHEMISTRY | 2016年 / 190卷

关键词：

Fructooligosaccharides; Flow chemistry; Cladosporium cladosporioides; Dried alginate entrapped enzymes (DALGEE); Prebiotics; BETA-FRUCTOFURANOSIDASE; INDUSTRIAL-PRODUCTION; COLONIZATION; RESOLUTION; GLUCOSE; CELLS;

D O I：

10.1016/j.foodchem.2015.06.002

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A sustainable and scalable process for the production of a new mixture of fructooligosaccharides (FOS) was developed using a continuous-flow approach based on an immobilized whole cells-packed bed reactor. The technological transfer from a classical batch system to an innovative flow environment allowed a significant improvement of the productivity. Moreover, the stability of this production system was ascertained by up to 7 days of continuous working. These results suggest the suitability of the proposed method for a large-scale production of the desired FOS mixture, in view of a foreseeable use as a novel prebiotic preparation. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：607 / 613

页数：7

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