Isolation and biological properties of polysaccharide CPS-1 from cultured Cordyceps militaris

被引：133
|
作者：
Yu, RM [1 ]
Song, LY
Zhao, Y
Bin, W
Wang, L
Zhang, H
Wu, YH
Ye, WC
Yao, XS
机构：
[1] Jinan Univ, Coll Pharm, Dept Nat Prod Chem, Guangzhou 510632, Peoples R China
[2] Zhejiang Univ, Coll Pharmaceut Sci, Dept Tradit Chinese Med & Nat Drug Res, Hangzhou 310031, Peoples R China
[3] Shenyang Pharmaceut Univ, Coll Tradit Chinese Med, Dept Nat Prod chem, Shenyang 110016, Peoples R China
来源：
FITOTERAPIA | 2004年 / 75卷 / 05期
关键词：
cordyceps militaris; tissue culture; polysaccharide; antiinflammatory activity; immunity function;
D O I：
10.1016/j.fitote.2004.04.003
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A polysaccharide from the water extract of cultured Cordyceps militaris was isolated through ethanol precipitation, deproteination and gel-filtration chromatography. Their molecular weight was determined using gel-filtration chromatography. The structure of polysaccharide CPS-1 was elucidated by sugar analysis, Smith degradation, IR and C-13-NMR spectroscopy. CPS-1 was shown to possess a significant antiinflammatory activity and suppressed the Immoral immunity in mice but had no significant effects on the cellular immunity and the non-specific immunity. (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码：465 / 472
页数：8
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