Isolation and biological properties of polysaccharide CPS-1 from cultured Cordyceps militaris

被引：133

作者：

Yu, RM ^{[1
]}

Song, LY

Zhao, Y

Bin, W

Wang, L

Zhang, H

Wu, YH

Ye, WC

Yao, XS

机构：

[1] Jinan Univ, Coll Pharm, Dept Nat Prod Chem, Guangzhou 510632, Peoples R China

[2] Zhejiang Univ, Coll Pharmaceut Sci, Dept Tradit Chinese Med & Nat Drug Res, Hangzhou 310031, Peoples R China

[3] Shenyang Pharmaceut Univ, Coll Tradit Chinese Med, Dept Nat Prod chem, Shenyang 110016, Peoples R China

来源：

FITOTERAPIA | 2004年 / 75卷 / 05期

关键词：

cordyceps militaris; tissue culture; polysaccharide; antiinflammatory activity; immunity function;

D O I：

10.1016/j.fitote.2004.04.003

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A polysaccharide from the water extract of cultured Cordyceps militaris was isolated through ethanol precipitation, deproteination and gel-filtration chromatography. Their molecular weight was determined using gel-filtration chromatography. The structure of polysaccharide CPS-1 was elucidated by sugar analysis, Smith degradation, IR and C-13-NMR spectroscopy. CPS-1 was shown to possess a significant antiinflammatory activity and suppressed the Immoral immunity in mice but had no significant effects on the cellular immunity and the non-specific immunity. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：465 / 472

页数：8

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