Significance of Paraprotein Gap and β2 microglobulins in Predialysis Population with Multiple Myeloma

被引：0
|
作者：
Ali, Hatem [1 ]
Kishore, Bhuvan [2 ]
Baharani, Jyoti [1 ]
机构：
[1] Heart England Teaching Hosp, Dept Renal Med, Birmingham, W Midlands, England
[2] Heart England Teaching Hosp, Dept Hematol, Birmingham, W Midlands, England
来源：
SAUDI JOURNAL OF KIDNEY DISEASES AND TRANSPLANTATION | 2019年 / 30卷 / 04期
关键词：
LONG-TERM MORTALITY; RENAL-FAILURE; GLOBULIN RATIO; ALBUMIN; SERUM; PROTEIN; BETA-2-MICROGLOBULIN; SURVIVAL; DISEASE; PATHOGENESIS;
D O I：
10.4103/1319-2442.265458
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Paraprotein gap is sometimes used as a screening tool in some autoimmune diseases, cancers, and screening for latent infections. The increase in the paraprotein gap in these diseases was hypothesized to be the result of increased levels of immunoglobulins, raising the total serum protein without any changes in serum albumin. Our aim was to assess the overall survival using novel chemotherapy, bortezomib compared to traditional ones and to assess if paraprotein gap could be used as a predictor of survival. Finally, we aimed to assess factors that could predict renal response in this population.
引用
收藏
页码：825 / 831
页数：7
相关论文
共 50 条
  • [41] Prognostic significance of chromosome aberrations in multiple myeloma
    Zubasheva, Ye. I.
    Obukhova, T. N.
    Andreyeva, N. Ye.
    Vodinskaya, L. A.
    Alimova, G. A.
    Varlamova, Ye. Yu.
    Kulikov, S. M.
    Domracheva, Ye. V.
    GEMATOLOGIYA I TRANSFUZIOLOGIYA, 2008, 53 (06): : 31 - 36
  • [42] THE SIGNIFICANCE OF URINE ELECTROPHORESIS IN PATIENTS WITH MULTIPLE MYELOMA
    ZINNEMAN, HH
    GLENCHUR, H
    GLEASON, DF
    ARCHIVES OF INTERNAL MEDICINE, 1960, 106 (02) : 172 - 178
  • [43] Functional significance of genetic abnormalities in multiple myeloma
    Gadó, K
    Domján, G
    Kormos, L
    Falus, A
    HAEMATOLOGIA, 2002, 32 (03) : 191 - 208
  • [44] Clinical significance of telomerase activity in multiple myeloma
    Shiratsuchi, M
    Muta, K
    Abe, Y
    Motomura, S
    Taguchi, F
    Takatsuki, H
    Uike, N
    Umemura, T
    Nawata, H
    Nishimura, J
    CANCER, 2002, 94 (08) : 2232 - 2238
  • [45] Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma
    Kyle, Robert A.
    Rajkumar, S. Vincent
    JAMA ONCOLOGY, 2015, 1 (02) : 174 - 175
  • [46] Monoclonal gammopathy of undetermined significance and multiple myeloma
    Schmalzing, M.
    Tony, H. -P.
    Knop, S.
    ZEITSCHRIFT FUR RHEUMATOLOGIE, 2017, 76 : 33 - 37
  • [47] Prognostic significance of FSCN family in multiple myeloma
    Deng, Cong
    Si, Chaozeng
    Ye, Xu
    Zhou, Qiang
    Zeng, Tiansheng
    Huang, Zeyong
    Huang, Wenhui
    Zhu, Pei
    Zhong, Qingfu
    Wu, Zhihua
    Zhu, Huoyan
    Lin, Qing
    Zhang, Wenjuan
    Fu, Lin
    Zheng, Yongjiang
    Qian, Tingting
    JOURNAL OF CANCER, 2021, 12 (07): : 1936 - 1944
  • [48] The significance of RB1 in multiple myeloma
    Wang, Yiwen
    Yang, Rui
    Liu, Rui
    Yang, Ruoyu
    Lin, Zujie
    He, Aili
    FRONTIERS IN IMMUNOLOGY, 2024, 15
  • [49] The clinical significance of cereblon expression in multiple myeloma
    Schuster, Steven R.
    Kortuem, K. Martin
    Zhu, Yuan Xiao
    Braggio, Esteban
    Shi, Chang Xin
    Bruins, Laura A.
    Schmidt, Jessica E.
    Ahmann, Greg
    Kumar, Shaji
    Rajkumar, S. Vincent
    Mikhael, Joseph
    LaPlant, Betsy
    Champion, Mia D.
    Laumann, Kristina
    Barlogie, Bart
    Fonseca, Rafael
    Bergsagel, P. Leif
    Lacy, Martha
    Stewart, A. Keith
    LEUKEMIA RESEARCH, 2014, 38 (01) : 23 - 28
  • [50] Significance of bone marrow fibrosis in multiple myeloma
    Subramanian, Rajiv
    Basu, Debdatta
    Dutta, Tarun K.
    PATHOLOGY, 2007, 39 (05) : 512 - 515
12345