Significance of Paraprotein Gap and β2 microglobulins in Predialysis Population with Multiple Myeloma

被引：0
|
作者：
Ali, Hatem [1 ]
Kishore, Bhuvan [2 ]
Baharani, Jyoti [1 ]
机构：
[1] Heart England Teaching Hosp, Dept Renal Med, Birmingham, W Midlands, England
[2] Heart England Teaching Hosp, Dept Hematol, Birmingham, W Midlands, England
来源：
SAUDI JOURNAL OF KIDNEY DISEASES AND TRANSPLANTATION | 2019年 / 30卷 / 04期
关键词：
LONG-TERM MORTALITY; RENAL-FAILURE; GLOBULIN RATIO; ALBUMIN; SERUM; PROTEIN; BETA-2-MICROGLOBULIN; SURVIVAL; DISEASE; PATHOGENESIS;
D O I：
10.4103/1319-2442.265458
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Paraprotein gap is sometimes used as a screening tool in some autoimmune diseases, cancers, and screening for latent infections. The increase in the paraprotein gap in these diseases was hypothesized to be the result of increased levels of immunoglobulins, raising the total serum protein without any changes in serum albumin. Our aim was to assess the overall survival using novel chemotherapy, bortezomib compared to traditional ones and to assess if paraprotein gap could be used as a predictor of survival. Finally, we aimed to assess factors that could predict renal response in this population.
引用
收藏
页码：825 / 831
页数：7
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