Significance of Paraprotein Gap and β2 microglobulins in Predialysis Population with Multiple Myeloma

被引：0
|
作者：
Ali, Hatem [1 ]
Kishore, Bhuvan [2 ]
Baharani, Jyoti [1 ]
机构：
[1] Heart England Teaching Hosp, Dept Renal Med, Birmingham, W Midlands, England
[2] Heart England Teaching Hosp, Dept Hematol, Birmingham, W Midlands, England
来源：
SAUDI JOURNAL OF KIDNEY DISEASES AND TRANSPLANTATION | 2019年 / 30卷 / 04期
关键词：
LONG-TERM MORTALITY; RENAL-FAILURE; GLOBULIN RATIO; ALBUMIN; SERUM; PROTEIN; BETA-2-MICROGLOBULIN; SURVIVAL; DISEASE; PATHOGENESIS;
D O I：
10.4103/1319-2442.265458
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Paraprotein gap is sometimes used as a screening tool in some autoimmune diseases, cancers, and screening for latent infections. The increase in the paraprotein gap in these diseases was hypothesized to be the result of increased levels of immunoglobulins, raising the total serum protein without any changes in serum albumin. Our aim was to assess the overall survival using novel chemotherapy, bortezomib compared to traditional ones and to assess if paraprotein gap could be used as a predictor of survival. Finally, we aimed to assess factors that could predict renal response in this population.
引用
收藏
页码：825 / 831
页数：7
相关论文
共 50 条
  • [21] MULTIPLE-MYELOMA AND THE ANION GAP
    SERRALLACH, CP
    GIL, JAB
    DURAN, JR
    BERGA, AP
    SOLANO, JT
    NAGORE, FJZ
    MEDICINA CLINICA, 1981, 77 (06): : 243 - 246
  • [22] ANION GAP IN MULTIPLE-MYELOMA
    PALADINI, G
    SALA, PG
    ACTA HAEMATOLOGICA, 1979, 62 (03) : 148 - 152
  • [23] MULTIPLE-MYELOMA AND ANION GAP
    MURRAY, T
    LONG, W
    NARINS, RG
    NEW ENGLAND JOURNAL OF MEDICINE, 1975, 292 (11): : 574 - 575
  • [24] A biased Gm haplotype and Gm paraprotein allotype in multiple myeloma suggests a role for the Gm system in myeloma development
    Ilic, V.
    Milosevic-Jovcic, N.
    Markovic, D.
    Petrovic, S.
    Stefanovic, G.
    INTERNATIONAL JOURNAL OF IMMUNOGENETICS, 2007, 34 (02) : 119 - 125
  • [25] Side Population of Multiple Myeloma and Multiple Myeloma Stem Cell
    Kim, Kyoung Ha
    Cheong, Hee-jeong
    Kim, Sook-ja
    Kim, Se Hyung
    Yoon, Jina
    Kim, Han Jo
    Kim, Hyun Jung
    Lee, Sang-Cheol
    Bae, Sang Byung
    Kim, Chan-Kyu
    Lee, Namsu
    Lee, Kyu Taeg
    Park, Sung Kyu
    Hong, Dae Sik
    Won, Jong-Ho
    Jun, Hyun Jung
    Chang, Myung Hee
    BLOOD, 2014, 124 (21)
  • [26] Association of a dominantly inherited hyperphosphorylated paraprotein target with sporadic and familial multiple myeloma and monoclonal gammopathy of undetermined significance: a case-control study
    Grass, Sandra
    Preuss, Klaus-Dieter
    Ahlgrimm, Manfred
    Fadle, Natalie
    Regitz, Evi
    Pfoehler, Claudia
    Murawski, Niels
    Pfreundschuh, Michael
    LANCET ONCOLOGY, 2009, 10 (10): : 950 - 956
  • [27] A STRUCTURALLY ABERRANT IMMUNOGLOBULIN PARAPROTEIN IN A PATIENT WITH MULTIPLE-MYELOMA AND CORNEAL CRYSTAL DEPOSITS
    GREEN, ED
    MORRISON, LK
    LOVE, PE
    DESCHRYVERKECSKEMETI, K
    WALTMAN, SR
    SMITH, ME
    SCOTT, MG
    AMERICAN JOURNAL OF MEDICINE, 1990, 88 (03): : 304 - 311
  • [28] A PATIENT WITH MULTIPLE-MYELOMA AND RESPIRATORY INSUFFICIENCY DUE TO ACCUMULATION OF PARAPROTEIN IN THE ALVEOLAR SPACE
    MEIJER, WG
    KOOY, MV
    LADDE, BE
    BRITISH JOURNAL OF HAEMATOLOGY, 1994, 87 (03) : 663 - 665
  • [29] MULTIPLE-MYELOMA ASSOCIATED WITH A-9S IGG PARAPROTEIN AND CARCINOMA OF PROSTATE
    CHIN, CK
    BARTON, BP
    SMITH, LL
    WRIGHT, CS
    MOORES, RR
    LUTCHER, CL
    CANCER, 1972, 30 (01) : 206 - &
  • [30] A PARAPROTEIN PHENOMENON EVIDENCED BY INTERFERENCE WITH CREATININE DETERMINATION IN SERA OF MULTIPLE-MYELOMA PATIENTS
    DATTA, P
    GRAHAM, G
    SCHOEN, I
    CLINICAL CHEMISTRY, 1984, 30 (06) : 968 - 968
12345