Ultrasonic Activated Efficient Synthesis of Indenopyrazolones via a One-Pot Multicomponent Reaction

被引:8
|
作者
Safari, Javad [1 ]
Nasab, Narges Hosseini [1 ]
机构
[1] Univ Kashan, Coll Chem, Dept Organ Chem, Lab Organ Compound Res, Kashan, Iran
关键词
Indenopyrazolone; multicomponent reactions; ninhydrin; ultrasound irradiation; 1,3-DIPOLAR CYCLOADDITIONS; CHEMISTRY; PYRAZOLES;
D O I
10.1080/10406638.2019.1678183
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A convenient and fast sonochemical methodology for the synthesis of indenopyrazolone derivatives via three-component reaction of benzaldehyde, phenylhydrazine, and ninhydrin in acetonitrile is described. A series of compounds were synthesized and characterized by FT-IR, (HNMR)-H-1 and CHN. This appropriate procedure includes several advantages such as short reaction times, room temperature, excellent yield with easy purification process and mild reaction conditions. In addition, ultrasonic irradiation vs. traditional heating or stirring conditions showed worthy superiority.
引用
收藏
页码:1383 / 1391
页数:9
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