One-pot synthesis of iodoindolizine derivatives via a novel multicomponent reaction

被引:5
|
作者
Yan, Peiyun [1 ]
Liu, Juanjuan [1 ]
Sun, Qian [1 ]
Yao, Juan [1 ]
Xue, Zhiheng [1 ]
Wang, Cunde [1 ]
机构
[1] Yangzhou Univ, Sch Chem & Chem Engn, Yangzhou 225002, Peoples R China
基金
中国国家自然科学基金;
关键词
multicomponent reaction; 1-iodoindolizine; 3-acylindolizine; acetophenone; molecular iodine; VOLATILE ORGANIC-COMPOUNDS; CALCIUM-ENTRY BLOCKERS; TOPOISOMERASE-I; LAMELLARIN-D; INDOLIZINES; INHIBITORS; ANNULATION; BEHAVIOR;
D O I
10.3184/174751913X13667371904771
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A one-pot reaction was developed to synthesise a variety of 1-iodoindolizines from substituted acetophenone, acetic acid, pyridine, and molecular iodine. The structure of 3-benzoyl-1-iodoindolizine (2a) and 1,3-dibenzoylindolizine (3a) was further confirmed by X-ray single crystal analysis.
引用
收藏
页码:323 / 326
页数:4
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