Facile and efficient synthesis of functionalized iminothiopyran and isothiochromen via one-pot multicomponent reactions

被引：12
|
作者：
Hamadi, Hosein [3 ]
Khoobi, Mehdi [4 ]
Hossaini, Zinatossadat [5 ]
Shafiee, Abbas [1 ,2 ]
机构：
[1] Univ Tehran Med Sci, Dept Chem, Fac Pharm, Tehran 14176, Iran
[2] Univ Tehran Med Sci, Pharmaceut Sci Res Ctr, Tehran 14176, Iran
[3] Tarbiat Modares Univ, Dept Chem, Tehran, Iran
[4] Zanjan Univ, Dept Chem, Zanjan, Iran
[5] Islamic Azad Univ, Dept Chem, Qaemshahr Branch, Mazandaran, Iran
来源：
MOLECULAR DIVERSITY | 2011年 / 15卷 / 01期
基金：
美国国家科学基金会;
关键词：
6H-6-iminothiopyran-2,3-dicarboxylate; Aryl isothiocyanate; Dialkyl acetylenedicarboxylate; 1H-isothiochromene-3,4-dicarboxylate; Multicomponent reaction; MCR; ANALOGS; ISOCYANIDES;
D O I：
10.1007/s11030-010-9230-0
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
An efficient synthesis of 6H-6-iminothiopyran-2,3-dicarboxylate and 1H-isothiochromene-3,4-dicarboxylate derivatives via one-pot reactions between acetylenic esters, aryl isothiocyanates and enaminones in dichloromethane at room temperature is described. The mild reaction condition, high yields and the new products are advantages of our method.
引用
收藏
页码：35 / 40
页数：6
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