Base-catalyzed α-vinylation of ketones with acetylenes as a key step in one-pot synthesis of pyrazolines and pyrazoles

被引：11

作者：

Schmidt, Elena Yu ^{[1
]}

Ivanova, Elena V. ^{[1
]}

Semenova, Nadezhda V. ^{[1
]}

Tatarinova, Inna V. ^{[1
]}

Ushakov, Igor A. ^{[1
]}

Trofimov, Boris A. ^{[1
]}

机构：

[1] Russian Acad Sci, Siberian Branch, AE Favorsky Irkutsk Inst Chem, Irkutsk 664033, Russia

来源：

MENDELEEV COMMUNICATIONS | 2015年 / 25卷 / 02期

关键词：

BUILDING-BLOCKS; ARYLACETYLENES; LIGANDS; STYRENE;

D O I：

10.1016/j.mencom.2015.03.018

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The sequential reaction of ketones with phenylacetylene in the presence of KOH/DMSO system followed by the treatment of the reaction mixture with HCl and monosubstituted hydrazines leads to pyrazolines and pyrazoles in up to 87% total yield.

引用

页码：131 / 132

页数：2

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