Synthesis of 4-aryl substituted 3,4-dihydropyrimidinones using silica-chloride under solvent free conditions

被引:89
|
作者
Karade, Hitendra N. [1 ]
Sathe, Manisha [1 ]
Kaushik, M. P. [1 ]
机构
[1] Def Res & Dev Estab, Proc Technol Dev Div, Disc Ctr, Gwalior 474002, MP, India
来源
MOLECULES | 2007年 / 12卷 / 07期
关键词
biginelli reaction; dihydropyrimidinones; silica chloride; solvent free;
D O I
10.3390/12071341
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This paper describes an improved procedure for the efficient and facile synthesis of 4-aryl substituted 3, 4-dihydropyrimidinones under mild reaction conditions with excellent yields using inexpensive silica chloride under solvent free conditions.
引用
收藏
页码:1341 / 1351
页数:11
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