H2SO4-Silica Catalyzed One-Pot and Efficient Synthesis of Dihydropyrimidinones Under Solvent-Free Conditions

被引：7

作者：

Pourmousavi, Seied Ali ^{[1
]}

Hasani, Maryam ^{[1
]}

机构：

[1] Damghan Univ, Sch Chem, Damghan 3671641167, Iran

来源：

E-JOURNAL OF CHEMISTRY | 2011年 / 8卷

关键词：

H2SO4-Silica; Aldehydes; 1,3-Dicarbonyl compounds; Dihydropyrimidinone; Biginelli reaction; Solvent free conditions; CALCIUM-CHANNEL BLOCKERS; HIGH-YIELD SYNTHESIS; REUSABLE CATALYST; SULFURIC-ACID; BIGINELLI REACTION; IMPROVED PROTOCOL; SILICA; 3,4-DIHYDROPYRIMIDIN-2(1H)-ONES; TRIBROMIDE; CHLORIDE;

D O I：

10.1155/2011/158612

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

H2SO4-Silica efficiently catalyzes the three-component condensation reaction of aldehydes, 1,3-dicarbonyl compounds and urea/thiourea under solvent free conditions to afford the corresponding dihydropyrimidinones and thio-derivatives in high yields. Compared to the classical Biginelli reaction conditions, this new method consistently has the advantage of giving good yields and requiring short reaction times.

引用

页码：S462 / S466

页数：5

共 50 条

[1] An efficient one-pot synthesis of dihydropyrimidinones catalyzed by zirconium hydrogen phosphate under solvent-free conditions
Besoluk, Senol
Kucukislamoglu, Mustafa
Zengin, Mustafa
Arslan, Mustafa
Nebioglu, Mehmet
[J]. TURKISH JOURNAL OF CHEMISTRY, 2010, 34 (03) : 411 - 416
[2] A facile and efficient one-pot synthesis of dihydropyrimidinones catalyzed by magnesium bromide under solvent-free conditions
Salehi, H
Guo, QX
[J]. SYNTHETIC COMMUNICATIONS, 2004, 34 (01) : 171 - 179
[3] An efficient one-pot synthesis of dihydropyrimidinones by a samarium diiodide catalyzed Biginelli reaction under solvent-free conditions
Han, XY
Xu, F
Luo, YQ
Shen, Q
[J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2005, 2005 (08) : 1500 - 1503
[4] NaIO4-catalyzed one-pot synthesis of dihydropyrimidinones at room temperature under solvent-free conditions
X. Jing
Z. Li
X. Pan
Y. Shi
C. Yan
[J]. Journal of the Iranian Chemical Society, 2009, 6 : 514 - 518
[5] NaIO4-Catalyzed One-Pot Synthesis of Dihydropyrimidinones at Room Temperature under Solvent-Free Conditions
Jing, X.
Li, Z.
Pan, X.
Shi, Y.
Yan, C.
[J]. JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2009, 6 (03) : 514 - 518
[6] An efficient and solvent-free one-pot synthesis of dihydropyrimidinones under microwave irradiation
Jiang, Cheng
You, Qi Dong
[J]. CHINESE CHEMICAL LETTERS, 2007, 18 (06) : 647 - 650
[7] An efficient and solvent-free one-pot synthesis of dihydropyrimidinones under microwave irradiation
Cheng Jiang
[J]. Chinese Chemical Letters, 2007, (06) : 647 - 650
[8] Benzyltriphenylphosphonium Chloride: An Efficient Catalyst for One-Pot Synthesis of Dihydropyrimidinones/thiones Under Solvent-Free Conditions
Alikarami, Mohammad
Moradi, Ronak
[J]. LETTERS IN ORGANIC CHEMISTRY, 2015, 12 (08) : 560 - 565
[9] H2SO4-silica as an efficient and chemoselective catalyst for the synthesis of acylal from aldehydes under solvent-free conditions
Pourmousavi, Seied Ali
Zinati, Zahra
[J]. TURKISH JOURNAL OF CHEMISTRY, 2009, 33 (03) : 385 - 392
[10] Zinc perchlorate catalyzed one-pot synthesis of 3,4-dihydropyrimidinones under solvent-free conditions
Palekar, Vikrant S.
Shukla, Sanjeev R.
[J]. GREEN CHEMISTRY LETTERS AND REVIEWS, 2008, 1 (03) : 185 - 190

← 1 2 3 4 5 →