Colorimetric detection of RNA fragments based on associated toehold-mediated reaction and gold nanoparticles

被引:2
|
作者
Zhang, Wantong [1 ]
Song, Juanjuan [1 ]
Zheng, Hongzheng [1 ]
Xu, Xiaowen [1 ]
机构
[1] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China
基金
中国国家自然科学基金;
关键词
DETECTION SYSTEM; AMPLIFICATION;
D O I
10.1039/d2cc02389j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Herein we report a reverse transcription-free, label-free and enzyme-free colorimetric method for RNA nucleic acid fragments detection. The method can conveniently determine the presence of dual gene targets and distinguish single nucleotide polymorphism by visual observation.
引用
收藏
页码:8666 / 8669
页数:4
相关论文
共 50 条
  • [21] Accelerating Toehold-Mediated DNA Strand Displacement Reaction using Polyquaternium
    Liu, Junlan
    Zhang, Qing
    CHEMISTRY-A EUROPEAN JOURNAL, 2025,
  • [22] Enhanced fluorescent detection of nucleic acid based on hairpin DNA-assisted toehold-mediated strand displacement reaction
    Liu, Yaojia
    Shi, Yantian
    Ding, Kexin
    Liu, Jing
    Wang, Haiyan
    Zhou, Hong
    SENSORS AND ACTUATORS B-CHEMICAL, 2023, 385
  • [23] A highly sensitive ratiometric electrochemical aptasensor for prostate specific antigen detection based on toehold-mediated strand displacement reaction
    Wang, Ping
    Guan, Zhimin
    Xie, Yaoyao
    Li, Sanqiang
    CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2024, 52 (03)
  • [25] Gold nanoparticle enhanced fluorescence anisotropy for the assay of single nucleotide polymorphisms (SNPs) based on toehold-mediated strand-displacement reaction
    Wang, Xinyi
    Zou, Mingjian
    Huang, Hongduan
    Ren, Yuqian
    Li, Limei
    Yang, Xiaoda
    Li, Na
    BIOSENSORS & BIOELECTRONICS, 2013, 41 : 569 - 575
  • [26] Dynamic monitoring of an enzymatically driven dissipative toehold-mediated strand displacement reaction
    Li, Shuang
    Zhao, Disong
    Yang, Fangfang
    Liu, Shufeng
    CHEMICAL COMMUNICATIONS, 2024, 60 (05) : 570 - 573
  • [27] Toehold-mediated strand displacement reaction triggered by nicked DNAzymes substrate for amplified electrochemical detection of lead ion
    Zhao, Jianmin
    Zheng, Ting
    Gao, Jiaxi
    Xu, Wenju
    ELECTROCHIMICA ACTA, 2018, 274 : 16 - 22
  • [28] A universal ratiometric method for Micro-RNA detection based on the ratio of electrochemical/electrochemiluminescence signal, and toehold-mediated strand displacement amplification
    Niazi, Mohammad
    Azizi, Ava
    Khajavi, Zeynab
    Sheikh, Milad
    Taheri, Salman
    Radfar, Sasan
    Alizadeh, Abdolhamid
    Ghanbari, Reza
    ANALYTICA CHIMICA ACTA, 2023, 1257
  • [29] DNA and DNA computation based on toehold-mediated strand displacement reactions
    Guo, Yijun
    Wei, Bing
    Sun, Xianbao
    Yao, Dongbao
    Zhou, Xiang
    Xiao, Shiyan
    Liang, Haojun
    INTERNATIONAL JOURNAL OF MODERN PHYSICS B, 2018, 32 (18):
  • [30] Colorimetric detection of melamine based on methanobactin-mediated synthesis of gold nanoparticles
    Xin, Jia-ying
    Zhang, Lan-xuan
    Chen, Dan-dan
    Lin, Kai
    Fan, Hong-chen
    Wang, Yan
    Xia, Chun-gu
    FOOD CHEMISTRY, 2015, 174 : 473 - 479