Colorimetric detection of RNA fragments based on associated toehold-mediated reaction and gold nanoparticles

被引：2
|
作者：
Zhang, Wantong [1 ]
Song, Juanjuan [1 ]
Zheng, Hongzheng [1 ]
Xu, Xiaowen [1 ]
机构：
[1] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2022年 / 58卷 / 62期
基金：
中国国家自然科学基金;
关键词：
DETECTION SYSTEM; AMPLIFICATION;
D O I：
10.1039/d2cc02389j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Herein we report a reverse transcription-free, label-free and enzyme-free colorimetric method for RNA nucleic acid fragments detection. The method can conveniently determine the presence of dual gene targets and distinguish single nucleotide polymorphism by visual observation.
引用
收藏
页码：8666 / 8669
页数：4
相关论文
共 50 条
  • [41] Toehold-mediated strand displacement reaction-propelled cascade DNAzyme amplifier for microRNA let-7a detection
    Na Wang
    Yongjian Jiang
    Kunhan Nie
    Di Li
    Hui Liu
    Jian Wang
    Chengzhi Huang
    Chunmei Li
    ChineseChemicalLetters, 2023, 34 (06) : 241 - 244
  • [42] Selective Detection of Dengue Virus Serotypes Using Tandem Toehold-Mediated Displacement Reactions
    Gao, Mingxuan
    Waggoner, Jesse J.
    Hecht, Sidney M.
    Chen, Shengxi
    ACS INFECTIOUS DISEASES, 2019, 5 (11): : 1907 - 1914
  • [43] Highly Selective Detection of Single-Nucleotide Polymorphisms Using a Quartz Crystal Microbalance Biosensor Based on the Toehold-Mediated Strand Displacement Reaction
    Wang, Dingzhong
    Tang, Wei
    Wu, Xiaojie
    Wang, Xinyi
    Chen, Gengjia
    Chen, Qiang
    Li, Na
    Liu, Feng
    ANALYTICAL CHEMISTRY, 2012, 84 (16) : 7008 - 7014
  • [44] Electrochemical Biosensing Platform Based on Toehold-Mediated Strand Displacement Reaction and DSN Enzyme-Assisted Amplification for Two-Target Detection
    Yu, Linying
    Peng, Yao
    Sheng, Mengting
    Wang, Qian
    Jin, Zhiying
    Huang, Jianshe
    Yang, Xiurong
    ACS APPLIED MATERIALS & INTERFACES, 2024, 16 (34) : 45695 - 45703
  • [45] Ultrasensitive chemiluminescence assay for the lung cancer biomarker cytokeratin 21-1 via a dual amplification scheme based on the use of encoded gold nanoparticles and a toehold-mediated strand displacement reaction
    Hun, Xu
    Liu, Bingru
    Meng, Yan
    MICROCHIMICA ACTA, 2017, 184 (10) : 3953 - 3959
  • [46] DNA and DNA computation based on toehold-mediated strand-displacement reactions
    Xiao Shi-Yan
    Liang Hao-Jun
    ACTA PHYSICA SINICA, 2016, 65 (17)
  • [47] A highly sensitive and versatile fluorescent biosensor for pathogen nucleic acid detection based on toehold-mediated strand displacement initiated primer exchange reaction
    Zhang, Ye
    Li, Zihua
    Su, Wanting
    Zhong, Guangzhi
    Zhang, Xiaohe
    Wu, Yuan
    Situ, Bo
    Xiao, Yunju
    Yan, Xiaohui
    Zheng, Lei
    ANALYTICA CHIMICA ACTA, 2022, 1221
  • [48] Colorimetric Detection of Reducing Sugar Based on Gold Nanoparticles via Click-reaction
    Li Yan-Ping
    Jiang Ling
    Zhang Tao
    Tian Dan-Bi
    Huang He
    CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2013, 41 (11) : 1688 - 1693
  • [49] Ultrasensitive chemiluminescence assay for the lung cancer biomarker cytokeratin 21-1 via a dual amplification scheme based on the use of encoded gold nanoparticles and a toehold-mediated strand displacement reaction
    Xu Hun
    Bingru Liu
    Yan Meng
    Microchimica Acta, 2017, 184 : 3953 - 3959
  • [50] Electrochemical aptamer-based determination of protein tyrosine kinase-7 using toehold-mediated strand displacement amplification on gold nanoparticles and graphene oxide
    Li, Zongbing
    Zhou, Zhengkun
    Xue, Ning
    Wu, Shujie
    Miao, Xiangmin
    MICROCHIMICA ACTA, 2019, 186 (11)
12345